1226-64-8

Basic information

• Product Name: 1,3-bis(2-methoxyphenyl)thiourea
• Synonyms: 1,3-Bis(2-methoxyphenyl)thiourea; N,N'-di(2-methoxyphenyl)thiourea; thiourea, N,N'-bis(2-methoxyphenyl)-
• CAS NO: 1226-64-8
• Molecular Formula: C₁₅H₁₆N₂O₂S
• Molecular Weight: 288.3647
• Mol File: 1226-64-8.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 416.6°C at 760 mmHg
• Flash Point: 205.7°C
• Density: 1.277g/cm³
• Vapor Pressure: 3.78E-07mmHg at 25°C
• Refractive Index: 1.683
• CAS DataBase Reference: 1,3-bis(2-methoxyphenyl)thiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-bis(2-methoxyphenyl)thiourea(1226-64-8)
• EPA Substance Registry System: 1,3-bis(2-methoxyphenyl)thiourea(1226-64-8)

Safety Data

• Hazardous Substances Data: 1226-64-8(Hazardous Substances Data)

Usage

General Description

1,3-bis(2-methoxyphenyl)thiourea, also known as Methoxyphenylthiourea, is a chemical compound with the molecular formula C15H16N2OS. It is a thiourea derivative that is used in various research and industrial applications. It has been studied for its potential antitumor and antithyroid properties, as well as its use as a corrosion inhibitor in metal surfaces. It has also been used in the synthesis of various organic compounds, and as a reagent in organic chemistry reactions. 1,3-bis(2-methoxyphenyl)thiourea is a white to off-white solid with a melting point of approximately 190-193°C, and it is soluble in organic solvents like ethanol and acetone. It is important to handle this chemical with caution and in accordance with safety guidelines, as it may cause irritation to the skin, eyes, and respiratory system upon exposure.

Upstream product

• 91-23-6 2-Nitroanisole 
• 333-20-0 potassium thioacyanate 
• 90-04-0 2-methoxy-phenylamine 
• 119650-93-0 N-(o-methoxyphenyl)-As,As-di-p-tolylarsinous amide 
• 534-18-9 sodium trithiocarbonate 
• 75-15-0 carbon disulfide 
• 3288-04-8 1-isothiocyanato-2-methoxybenzene 
• 1147550-11-5 ammonium thiocyanate 
• 17356-08-0 thiourea 

Downstream Products

• 248279-10-9 N,N'-bis-(2-methoxy-phenyl)-S-methyl-isothiourea 
• 35251-94-6 (2-methoxy-phenyl)-[3-(2-methoxy-phenyl)-6-nitro-3H-thiazolo[4,5-b]quinoxalin-2-ylidene]-amine 
• 42748-49-2 (2-methoxy-phenyl)-[3-(2-methoxy-phenyl)-4-methyl-3H-thiazol-2-ylidene]-amine 
• 130255-89-9 4-(o-Methoxyphenyl)-5-(o-methoxyphenylimino)-1,2,4-dithiazolidin-3-on 
• 82694-30-2 [4-Ethyl-3-(2-methoxy-phenyl)-5-methyl-3H-thiazol-(2Z)-ylidene]-(2-methoxy-phenyl)-amine 
• 10541-78-3 2-methoxy-N-methylaniline 
• 90-04-0 2-methoxy-phenylamine 
• 931098-74-7 5-benzylidene-2-(o-methoxyphenyl)imino-3-(o-methoxyphenyl)-thiazolidin-4-one 
• 20220-77-3 1,3-bis(o-methoxyphenyl)carbodiimide 
• 23233-42-3 3-N-(2-methoxyphenyl),2-N'-(2-methoxyphenyl)iminothiazolidin-4-one 
• 3288-04-8 1-isothiocyanato-2-methoxybenzene 
• 6268-03-7 N,N'-bis(2-methoxyphenyl)-Guanidine 
• 85788-85-8 1,3-bis-(2-methoxy-phenyl)-2-thio-barbituric acid 

Relevant articles and documents

Alkaline earth metal complexes stabilized by amidine and guanidine ligands: Synthesis, structure and their catalytic activity towards polymerization of: Rac-lactide

A series of amidine ligands RAmDIPP (R is backbone substituent, R = 2-methylpyridine (HL1), N,N,2-trimethylaniline (HL2), N,N-dimethylpropan-1-amine (HL3); DIPP (2,6-diisopropylphenyl) is N substituent) and a (Z

Synthesis, molecular and solid state structure of 5-(5-nitro furan-2-ylmethylen), 3-N-(2-methoxy phenyl), 2-N′-(2-methoxyphenyl) imino thiazolidin-4-one: X-ray powder diffraction and DFT studies

The 5-(5-nitro furan-2-ylmethylen), 3-N-(2-methoxy phenyl), 2-N′-(2-methoxyphenyl) imino thiazolidin-4-one compound has been synthesized and fully characterized by FT-IR, 1H and 13C NMR spectroscopy. The crystal structure of the titl

A simple and straightforward synthesis of phenyl isothiocyanates, symmetrical and unsymmetrical thioureas under ball milling

Promoted by KOH under ball milling, anilines were efficiently transformed into isothiocyanates (in presence of 5.0 equiv. CS2) or symmetrical thioureas (in presence of 1.0 equiv. CS2), without using any other harsh or toxic decomposition reagent. Some in situ generated isothiocyanates can directly "click" with other amines to afford unsymmetrical thioureas.