122111-05-1 Usage
Description
4-Amino-1-(2-deoxy-2,2-difluoro-a-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone Hydrochloride, also known as 1'-Epi Gemcitabine Hydrochloride, is an α-anomer of Gemcitabine. It is a pale-yellow solid with unique chemical properties that make it a significant impurity in the synthesis of Gemcitabine.
Uses
Used in Pharmaceutical Industry:
4-Amino-1-(2-deoxy-2,2-difluoro-a-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone Hydrochloride is used as an impurity standard for the quality control and analysis of Gemcitabine in the pharmaceutical industry. Its presence as an α-anomer of Gemcitabine is crucial for ensuring the purity and efficacy of the final drug product.
Used in Research and Development:
In the field of research and development, 4-Amino-1-(2-deoxy-2,2-difluoro-a-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone Hydrochloride serves as a valuable compound for studying the synthesis, properties, and potential applications of Gemcitabine and its analogs. This helps in the development of new drugs and therapies based on Gemcitabine's structure and mechanism of action.
Check Digit Verification of cas no
The CAS Registry Mumber 122111-05-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,1,1 and 1 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 122111-05:
(8*1)+(7*2)+(6*2)+(5*1)+(4*1)+(3*1)+(2*0)+(1*5)=51
51 % 10 = 1
So 122111-05-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H11F2N3O4.ClH/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17;/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17);1H/t4-,6+,7+;/m1./s1
122111-05-1Relevant articles and documents
PREPARATION OF GEMCITABINE
-
Page/Page column 21, (2008/06/13)
A process for preparation of gemcitabine hydrochloride and purification thereof.
