121952-97-4

Basic information

• Product Name: 5-BENZYL-1,3-THIAZOL-2-AMINE
• Synonyms: 5-benzyl-1,3-thiazol-2-amine(SALTDATA: HCl);5-benzylthiazol-2-amine
• CAS NO: 121952-97-4
• Molecular Formula: C₁₀H₁₀N₂S
• Molecular Weight: 190.27
• Mol File: 121952-97-4.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 349.5°Cat760mmHg
• Flash Point: 165.2°C
• Appearance: /
• Density: 1.236g/cm³
• Vapor Pressure: 4.68E-05mmHg at 25°C
• Refractive Index: 1.652
• CAS DataBase Reference: 5-BENZYL-1,3-THIAZOL-2-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BENZYL-1,3-THIAZOL-2-AMINE(121952-97-4)
• EPA Substance Registry System: 5-BENZYL-1,3-THIAZOL-2-AMINE(121952-97-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 121952-97-4(Hazardous Substances Data)

Usage

General Description

5-Benzyl-1,3-thiazol-2-amine is a chemical compound with the molecular formula C11H10N2S. 5-BENZYL-1,3-THIAZOL-2-AMINE belongs to the class of organic compounds known as thiazoles, which are aromatic heterocyclic compounds containing a five-membered ring with the formula C3H3NS. 5-Benzyl-1,3-thiazol-2-amine is primarily used in the pharmaceutical and research industries, where it can be used as a building block in the synthesis of various pharmaceutical drugs and other organic compounds. It is also known for its potential biological activities and has been studied for its anti-inflammatory and anti-cancer properties. Additionally, this compound may also have applications in the field of materials science and as a ligand in coordination chemistry.

InChI:InChI=1/C10H10N2S/c11-10-12-7-9(13-10)6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H2,11,12)

Upstream product

• 19261-37-1 2-chloro-3-phenyl-propionaldehyde 
• 62-56-6 thiourea 
• 62-53-3 aniline 
• 104-53-0 3-phenyl-propionaldehyde 
• 51075-28-6 2-bromo-3-phenylpropanal 
• 17356-08-0 thiourea 
• 100-34-5 benzene diazonium chloride 
• 100-52-7 benzaldehyde 

Downstream Products

• 144836-50-0 ethyl 2-benzyl-6-phenylimidazo<2.1-b>thiazole-5-carboxylate 
• 144836-52-2 2-benzyl-6-phenylimidazo<2.1-b>thiazole 
• 121953-12-6 5-benzyl-3-p-fluorophenacyl-2-imino-2,3-dihydrothiazole 
• 919018-15-8 N-[5-benzyl-1,3-thiazol-2-yl]chromane-3-carboxamide 
• 301157-23-3 C₁₅H₁₂N₂O₂S 
• 1235559-89-3 N-(5-benzylthiazol-2-yl)decanamide 
• 1061161-52-1 N-(5-benzylthiazol-2-yl)-3-(furan-2-yl)propanamide 
• 267654-15-9 N-(5-benzylthiazol-2-yl)butyramide 
• 851722-11-7 C₁₃H₁₃ClN₂OS 
• 1353638-23-9 C₁₃H₁₁N₃OS₂ 
• 301306-13-8 N-(5-Benzyl-thiazol-2-yl)-2-chloro-acetamide 
• 923679-02-1 N-(5-benzyl-1,3-thiazol-2-yl)-5-methyl-1-phenyl-1H-1,2,3-triazole-4-carboxamide 
• 871323-56-7 N-(5-benzyl-1,3-thiazol-2-yl)-1-(2-methoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide 

Relevant articles and documents

Proapoptotic effects of novel thiazole derivative on human glioma cells

The aim of the present study was to investigate the antiproliferative and proapoptotic actions of N-(5-benzyl-1,3-thiazol-2-yl)-3,5-dimethyl-1-benzofuran-2-carboxamide derivative (compound 5) in glioma cells in comparison with the actions of temozolomide

Synthesis, structural characterization and thermal studies of a novel reagent 1-[(5-benzyl-1,3-thiazol-2-yl)diazenyl]naphthalene-2-ol

A new thiazolylazo reagent 1-[(5-benzyl-1,3-thiazol-2-yl)diazenyl]naphthalene-2-ol has been synthesized via arylation of acrolein and further diazotization and diazocoupling with 2-naphthol. The chemical structure of the compound was confirmed by IR, NMR:

COMPOUNDS AND USES THEREOF

The present invention features compounds useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.

SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF

Provided herein are small molecule activators of Nicotinamide Phosphoribosyltransferase (NAMPT), compositions comprising the compounds, and methods of using the compounds and compositions.