121-25-5 Usage
Description
Amprolium, an organic chloride salt with the chemical structure 1-[(4-amino-2-propylpyrimidin-5-yl)methyl]-2-methylpyridin-1-ium as the counterion, is an antiprotozoal agent known for its effectiveness in preventing coccidiosis in poultry and cattle. It is a solid substance with a significant role in the veterinary industry.
Uses
Used in Poultry Industry:
Amprolium is used as a coccidiostat for the prevention of coccidiosis in poultry. It helps to protect birds from the harmful effects of this parasitic disease, which can lead to significant economic losses in the poultry sector.
Used in Cattle Industry:
Amprolium is also used as a coccidiostat for the prevention of coccidiosis in cattle. By preventing this disease, it contributes to the overall health and productivity of the cattle population.
Brand Names:
Some of the well-known brand names for Amprolium in the veterinary industry include Amprol [Veterinary] (Merial), Amprovine [Veterinary] (Merial), and Corid [Veterinary] (Merial). These products are specifically designed to cater to the needs of the poultry and cattle industries, ensuring the health and well-being of these animals.
Originator
Neoprol ,SIMB
Manufacturing Process
1.9 grams of p-toluene sulfonyl chloride was added gradually with shaking to
a cooled (0-5°C) solution of 1.67 grams of 2-n-propyl-4-amino-5-hydroxymethyl
pyrimidine in 10 ml of 2-methylpyridine. The reaction mixture, after standing three hours in an ice bath, and 15 hours at room temperature, was
evaporated to dryness in vacuo. The residue was dissolved in 20 ml of water,
acidified with hydrochloric acid and poured over a column of Amberlite IRA-
400 ion exchange resin on the chloride cycle. The eluate was evaporated to
dryness to give a residue of 1-(2-n-propyl-4-amino-5-pyrimidylmethyl)-2-
methyl pyridinium chloride hydrochloride. On recrystallization from a
methanol-ethanol mixture, the quaternary had melting point 246°C (dec.).
Therapeutic Function
Coccidiostatic
Contact allergens
Amprolium is an antiprotozoal agent used for the prevention
of coccidiosis in poultry.
Safety Profile
When heated to
decomposition emits toxic fumes of Cl-.
Check Digit Verification of cas no
The CAS Registry Mumber 121-25-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,2 and 1 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 121-25:
(5*1)+(4*2)+(3*1)+(2*2)+(1*5)=25
25 % 10 = 5
So 121-25-5 is a valid CAS Registry Number.
InChI:InChI=1/C14H19N4.ClH/c1-3-6-13-16-9-12(14(15)17-13)10-18-8-5-4-7-11(18)2;/h4-5,7-9H,3,6,10H2,1-2H3,(H2,15,16,17);1H/q+1;/p-1