120595-80-4 Usage
Description
ACETAMINOPHEN GLUCURONIDE SODIUM SALT, also known as A161220 or Paracetamol, is the major urinary metabolite of Acetaminophen found in humans. It is an off-white crystalline solid that plays a significant role in the metabolism and excretion of Acetaminophen.
Uses
Used in Pharmaceutical Industry:
ACETAMINOPHEN GLUCURONIDE SODIUM SALT is used as a metabolite marker for monitoring the metabolism and excretion of Acetaminophen (Paracetamol) in humans. This helps in understanding the pharmacokinetics and safety profile of Acetaminophen, which is widely used as an analgesic and antipyretic drug.
Used in Toxicology and Drug Overdose:
ACETAMINOPHEN GLUCURONIDE SODIUM SALT is used as a biomarker for detecting and assessing Acetaminophen overdose in patients. High levels of this metabolite in urine can indicate potential liver damage or toxicity due to excessive consumption of Acetaminophen.
Used in Research and Development:
ACETAMINOPHEN GLUCURONIDE SODIUM SALT is used as a research compound for studying the metabolic pathways and mechanisms of Acetaminophen in the human body. This aids in the development of new drugs and therapies related to pain management and fever reduction.
Check Digit Verification of cas no
The CAS Registry Mumber 120595-80-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,5,9 and 5 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 120595-80:
(8*1)+(7*2)+(6*0)+(5*5)+(4*9)+(3*5)+(2*8)+(1*0)=114
114 % 10 = 4
So 120595-80-4 is a valid CAS Registry Number.
InChI:InChI=1/C14H17NO8.Na/c1-6(16)15-7-2-4-8(5-3-7)22-14-11(19)9(17)10(18)12(23-14)13(20)21;/h2-5,9-12,14,17-19H,1H3,(H,15,16)(H,20,21);/q;+1/p-1/t9-,10-,11+,12-,14-;/m1./s1
120595-80-4Relevant articles and documents
Preparation and characterisation of solid state forms of paracetamol-O-glucuronide
Hayes, John A.,Eccles, Kevin S.,Lawrence, Simon E.,Moynihan, Humphrey A.
experimental part, p. 108 - 112 (2012/03/22)
The synthesis and crystallisation of the pharmaceutically important metabolite, paracetamol-O-glucuronide, is described. Hydrated and anhydrous forms of the target molecule have been characterised by PXRD, DSC and TGA. In addition, a methanol solvate has
