1205098-83-4

Basic information

• Product Name: 1-(2,3-dihydrobenzofuran-4-yl)-2-propen-1-one
• Synonyms: 1-(2,3-dihydrobenzofuran-4-yl)-2-propen-1-one
• CAS NO: 1205098-83-4
• Molecular Weight: 174.199
• Mol File: 1205098-83-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2,3-dihydrobenzofuran-4-yl)-2-propen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,3-dihydrobenzofuran-4-yl)-2-propen-1-one(1205098-83-4)
• EPA Substance Registry System: 1-(2,3-dihydrobenzofuran-4-yl)-2-propen-1-one(1205098-83-4)

Safety Data

• Hazardous Substances Data: 1205098-83-4(Hazardous Substances Data)

Upstream product

• 209256-42-8 2,3-dihydro-1-benzofuran-4-carbaldehyde 

Downstream Products

• 196597-78-1 1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one 

Relevant articles and documents

A thunder-US for amine preparation method for the synthesis of the key intermediate

The invention discloses a synthetic preparation method for a key intermediate of ramelteon 1,2,6,7-tretrahydro-8H-indeno[5,4-b]furan-8-one. According to the preparation method, by taking 2,3-dihydrobenzofuran-4-formaldehyde as an initial raw material, the key intermediate of ramelteon 1,2,6,7-tretrahydro-8H-indeno[5,4-b]furan-8-one is synthesized through Grignard reaction, oxidizing reaction and Nazarov cyclization reaction. The preparation method has the advantages of being high in reaction selectivity, few in side effects, high in total yield and quality, environmental-friendly, simple and convenient in process operation, high in stability and controllability and the like, and is suitable for industrial large-scaled production.