120465-56-7

Basic information

• Product Name: Benzoic acid, 4-(dimethoxymethyl)-
• CAS NO: 120465-56-7
• Molecular Formula: C10H12O4
• Molecular Weight: 196.203
• Mol File: 120465-56-7.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-(dimethoxymethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(dimethoxymethyl)-(120465-56-7)
• EPA Substance Registry System: Benzoic acid, 4-(dimethoxymethyl)-(120465-56-7)

Safety Data

• Hazardous Substances Data: 120465-56-7(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 619-21-6 m-formylphenyl benzoic acid 
• 619-66-9 4-Carboxybenzaldehyde 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 166518-43-0 1-<4-(Dimethoxymethyl)phenyl>ethanone 
• 914292-52-7 C₂₂H₁₈⁽²⁾H₇NO₅ 
• 848420-57-5 4-Formyl-N-furan-2-ylmethylbenzamide 
• 1137575-49-5 N-[2-(2-chloroethoxy)ethyl]-4-formylbenzamide 
• 1093837-57-0 C₂₀H₃₁NO₅S₂ 
• 1613439-27-2 C₄₂H₆₆N₂O₅ 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 1076199-23-9 tert-butyl 4-(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)piperazine-1-carboxylate 
• 404844-02-6 N-Desmethyl Imatinib 
• 1059147-21-5 4-(dimethoxymethyl)-N'-phenylbenzohydrazide 
• 591208-39-8 (S,S)-N-(4-dimethoxymethyl-benzoyl)proline-cyclohexylalanine carboxylic acid hydrazide 

Relevant articles and documents

Cyclic acetals as cleavable linkers for affinity capture

Labeling proteins with biotin is a widely used method to identify target proteins due to biotin's strong binding affinity for streptavidin. Combined with alkyne-azide cycloaddition, which enables the coupling of probes to targeted proteins, biotin tags linked to an alkyne or azide have become a powerful tool for purification and analysis of proteins in proteomics. However, biotin requires harsh elution conditions to release the captured protein from the bead matrix. Use of these conditions reduces signal to noise and complicates the analysis. To improve affinity capture, cleavable linkers have been introduced. Here, we demonstrate the use of a cyclic acetal biotin probe that is prepared easily from commercially available starting materials, is stable to cell lysates, yet is cleaved under mildly acidic conditions, and which provides an aldehyde for further elaboration of the protein, if desired.

Haptens, antigens and antibodies of imatinib and N-demethylated imatinib and application thereof

The invention relates to the technical field of immunological detection, and particularly discloses haptens, antigens and antibodies of imatinib and N-demethylated imatinib and application of the haptens, the antigens and the antibodies, the structure of

A General Access to Propargylic Ethers through Br?nsted Acid Catalyzed Alkynylation of Acetals and Ketals with Trifluoroborates

A general Br?nsted acid catalyzed methodology for the alkynylation of acetals and ketals with alkynyltrifluoroborate salts has been developed. The reaction proceeds rapidly to afford valuable synthetic building block propargylic ethers in good to excellent yields. Unlike Lewis acid catalyzed transformations of trifluoroborates, this approach does not proceed via unstable organodifluoroborane intermediate. As a result, the developed methodology features excellent functional group tolerance and good atom economy. Br?nsted acid catalyzed alkynylation of acetals and ketals is described. Alkynyltrifluoroborate salts react rapidly to afford propargylic ethers. Organodifluoroborane, which is a common intermediate in Lewis acid catalyzed reactions of trifluoroborates, has not been observed. The reaction exhibits generally high yields and excellent functional group tolerance.