119410-08-1

Basic information

• Product Name: 3-HYDROXY DESLORATADINE HCL
• Synonyms: 3-HYDROXY DESLORATADINE HCL;8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-3-ol;Sch 45581;8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-β]pyridin-3-ol;5H-Benzo[5,6]cyclohepta[1,2-b]pyridin-3-ol, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-;3-OH-desloratadine-D4 Hbr;Loratadine Desethoxycarbonyl 3-Hydroxy IMpurity;Desloratadine 3-Hydroxy Impurity
• CAS NO: 119410-08-1
• Molecular Formula: C19H19ClN2O
• Molecular Weight: 326.82
• Product Categories: Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Heterocycles
• Mol File: 119410-08-1.mol
• Article Data: 0

Chemical Properties

• Melting Point: 169-171°C
• Boiling Point: 575.2°C at 760 mmHg
• Flash Point: 301.67°C
• Appearance: /
• Density: 1.292
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.647
• Storage Temp.: -20?C Freezer, Under Inert Atmosphere
• PKA: 9.27±0.20(Predicted)
• CAS DataBase Reference: 3-HYDROXY DESLORATADINE HCL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-HYDROXY DESLORATADINE HCL(119410-08-1)
• EPA Substance Registry System: 3-HYDROXY DESLORATADINE HCL(119410-08-1)

Safety Data

• Hazardous Substances Data: 119410-08-1(Hazardous Substances Data)

Usage

Description

3-Hydroxy Desloratadine HCL, also known as 3-Hydroxy Desloratadine, is an active metabolite of Loratadine, a second-generation antihistamine used for treating allergic symptoms. It is a light brown solid with chemical properties that contribute to its effectiveness in managing allergic reactions.

Uses

Used in Pharmaceutical Industry:
3-Hydroxy Desloratadine HCL is used as an active metabolite for [application reason]. It is utilized in the development of antihistamine medications to provide relief from allergic symptoms such as sneezing, itching, and runny nose. Its effectiveness in treating allergies is attributed to its ability to block the action of histamine, a compound responsible for allergic reactions.
Used in Allergy Treatment:
3-Hydroxy Desloratadine HCL is used as an antihistamine for [application reason]. It is particularly effective in treating seasonal allergies, such as hay fever, and other allergic conditions like hives and itching. Its use in allergy treatment helps to alleviate the discomfort and inconvenience caused by allergic reactions, improving the quality of life for those affected by allergies.
Used in Research and Development:
3-Hydroxy Desloratadine HCL is used as a research compound for [application reason]. It serves as a valuable tool for scientists and researchers in the pharmaceutical industry to study the mechanisms of action of antihistamines and develop new drugs with improved efficacy and safety profiles. Its role in research and development contributes to the advancement of allergy treatments and the understanding of allergic diseases.

InChI:InChI=1/C19H19ClN2O/c20-15-3-4-17-13(9-15)1-2-14-10-16(23)11-22-19(14)18(17)12-5-7-21-8-6-12/h3-4,9-11,21,23H,1-2,5-8H2