1191933-01-3Relevant articles and documents
Novel crystal form of prasugrel disulfate and preparation method of novel crystal form
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Paragraph 0032-0056, (2018/05/16)
The invention discloses a novel crystal of prasugrel disulfate (of formula II as shown in the specification), and a preparation method of the novel crystal or crystal thereof. The preparation method of the prasugrel disulfate or the crystal thereof has the advantages that operation conditions are simple and easy to control, XRD (X-Ray Diffraction) spectrums show that a product is high in crystallization degree, relatively large in crystal particle size and smooth in crystal surface, a rapid filtering and drying speed is achieved, the efficiency of the preparation process is improved, and an application of the novel crystal in medicine preparation is relatively well facilitated.
NOVEL POLYMORPHIC FORM OF PRASUGREL-HYDROGEN SULFATE
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Page/Page column 14, (2011/04/14)
Disclosed are: a novel polymorphic form of prasugrel-hydrogen sulfate having improved physical and pharmaceutical properties, a preparation method thereof, and a pharmaceutical composition for preventing or treating an ischemic disease comprising the same.
CRYSTALLINE FORMS OF PRASUGREL SALTS
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Page/Page column 24-25, (2011/10/31)
Salts of prasugrel were prepared including, for example, crystalline forms of prasugrel hydrobromide. These salts are useful, for example, in medicaments that inhibit the aggregation of platelets.