119020-88-1Relevant articles and documents
N-(α-Amidoalkyl)benzotriazole-mediated synthesis of β′-amido β-diketones: a general synthetic protocol for N-[β-(3,5-di and 1,3,5-trisubstituted pyrazol-4-yl)alkyl] amides
?elik, Ilhami,Kani?kan, Nevin,K?kten, ?ule
body text, p. 328 - 335 (2009/04/06)
Various β′-amido-β-diketones were first synthesized with N-(α-amidoalkyl)benzotriazole-mediated amidoalkylation of 1,3-diketones in moderate yields. These intermediates undergo rapid condensation with hydrazines to give the corresponding N-[β-(3,5-di and
N-(1-Benzotriazol-1-ylalkyl)amides, Versatile α-Amidoalkylation Reagents. 1. α-Amidoalkylation of CH Acids
Katritzky, Alan R.,Pernak, Juliusz,Fan, Wei-Qiang,Saczewski, Franciszek
, p. 4439 - 4443 (2007/10/02)
N-(1-Benzotriazol-1-ylalkyl)amides 2, easily prepared from an amide and an aldehyde with benzotriazole, react smoothly with CH acids under mild conditions to give the α-amidoalkylation products in good yields.Benzotriazole aminals also react with CH acids in the presence of methyl iodide.