1185133-81-6

Basic information

• Product Name: FLURBIPROFEN-D3
• Synonyms: FLURBIPROFEN-D3;2-Fluoro-a-trideuteromethyl-[1,1biphenyl]-4-acetic Acid,;2-Fluoro-α-(Methyl-d3)-[1,1'-biphenyl]-4-acetic Acid;2-Fluoro-α-(Methyl-d3)-4-diphenylacetic Acid;3-Fluoro-4-phenylhydratropic Acid-d3
• CAS NO: 1185133-81-6
• Molecular Formula: C15H13FO2
• Molecular Weight: 244.2609232
• Product Categories: Isotope Labeled Compounds;Aromatics;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals
• Mol File: 1185133-81-6.mol
• Article Data: 0

Chemical Properties

• Melting Point: 108-110°C
• Appearance: /
• Storage Temp.: -20°C Freezer
• CAS DataBase Reference: FLURBIPROFEN-D3(CAS DataBase Reference)
• NIST Chemistry Reference: FLURBIPROFEN-D3(1185133-81-6)
• EPA Substance Registry System: FLURBIPROFEN-D3(1185133-81-6)

Safety Data

• Hazardous Substances Data: 1185133-81-6(Hazardous Substances Data)

Usage

Description

Flurbiprofen-d3, an isotopically labeled analog of Flurbiprofen, is a white solid substance designed for use as an internal standard in the quantification of flurbiprofen by gas chromatography-mass spectrometry (GC-MS) or liquid chromatography-mass spectrometry (LC-MS). It serves as a valuable tool in the analysis and measurement of flurbiprofen levels in various applications.

Uses

Used in Pharmaceutical Industry:
Flurbiprofen-d3 is used as an internal standard for the quantification of flurbiprofen in pharmaceutical research and development. This application aids in the accurate measurement of flurbiprofen levels, ensuring the efficacy and safety of formulations containing flurbiprofen for managing pain and inflammation associated with arthritis.
Used in Research and Development:
Flurbiprofen-d3 is used as a research tool in the study of the pharmacological effects of flurbiprofen, a non-selective COX inhibitor. It helps researchers understand the mechanisms of action, such as its reduction of carrageenan-induced hind paw edema and yeast-induced fever in rats, as well as its effects on plasma fibrinogen levels and arthritic score in a rat model of adjuvant-induced arthritis.
Used in Cancer Research:
Flurbiprofen-d3 is used as a research tool in cancer research, particularly in the study of flurbiprofen's effects on tumor weight, prostaglandin production, and survival rates in a WHT-NC mouse xenograft model. This application aids in the development of potential therapeutic strategies for cancer treatment.
Used in Analytical Chemistry:
Flurbiprofen-d3 is used as a reference material in the development and validation of analytical methods for the detection and quantification of flurbiprofen in various samples, such as biological fluids, pharmaceutical formulations, and environmental samples. This application ensures the accuracy and reliability of analytical results in different research and quality control settings.