118399-28-3 Usage
Description
Benzyl (R)-5-oxotetrahydrofuran-3-ylcarbamate, also known as 3(R)-[(Carbobenzyloxy)amino]-γ-butyrolactone (CAS# 118399-28-3), is an organic compound with off-white solid properties. It is primarily used in the field of organic synthesis due to its unique chemical structure and reactivity.
Uses
Used in Organic Synthesis:
Benzyl (R)-5-oxotetrahydrofuran-3-ylcarbamate is used as a synthetic intermediate for the development of various organic compounds. Its carbamate functional group allows for further chemical reactions and modifications, making it a versatile building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Benzyl (R)-5-oxotetrahydrofuran-3-ylcarbamate is used as a key component in the synthesis of drugs targeting specific medical conditions. Its unique structure and reactivity enable the development of novel therapeutic agents with improved efficacy and selectivity.
Used in Agrochemical Industry:
Benzyl (R)-5-oxotetrahydrofuran-3-ylcarbamate is also utilized in the agrochemical industry for the synthesis of new pesticides and other crop protection agents. Its incorporation into these products can lead to enhanced performance and selectivity, ultimately contributing to more effective and environmentally friendly agricultural practices.
Check Digit Verification of cas no
The CAS Registry Mumber 118399-28-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,3,9 and 9 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 118399-28:
(8*1)+(7*1)+(6*8)+(5*3)+(4*9)+(3*9)+(2*2)+(1*8)=153
153 % 10 = 3
So 118399-28-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H13NO4/c14-11-6-10(8-16-11)13-12(15)17-7-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H,13,15)/t10-/m1/s1
118399-28-3Relevant articles and documents
INHIBITING B-CELL LYMPHOMA 2 (BCL-2) AND RELATED PROTEINS
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Paragraph 00126, (2017/09/05)
Novel compounds inhibiting anti-apoptosis proteins B-cell lymphoma 2 (Bcl-2) and Bcl-XL include compounds of formula (I) and formula (II) disclosed herein, as well as liposome compositions comprising Bcl-2 inhibitor compounds. These compositions are usefu
CHEMICAL COMPOUNDS
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Page/Page column 9; 32, (2012/02/15)
The present invention relates to compounds of Formula (I): and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit Bcl-2 and/or Bcl-XL activities and may be used for the treatment of cancer.
Design and synthesis of some new quinoline-3-carbohydrazone derivatives as potential antimycobacterial agents
Eswaran, Sumesh,Adhikari, Airody Vasudeva,Pal, Nishith K.,Chowdhury, Imran H.
supporting information; experimental part, p. 1040 - 1044 (2010/06/14)
A series of 26 new quinoline derivatives carrying active pharmacophores has been synthesized and evaluated for their in vitro antituberculosis activity against Mycobacterium tuberculosis H37Rv (MTB), Mycobacterium smegmatis (MC2), and Mycobacterium fortuitum following the broth micro dilution assay method. Compounds 13e, 13i, 13k, 14a, 14c, 14i, and 14k exhibited significant minimum inhibition concentrations, when compared with first line drugs isoniazid (INH) and rifampicin (RIF) and could be ideally suited for further modifications to obtain more efficacious compounds in the fight against multi-drug resistant tuberculosis.