118249-08-4 Usage
Description
1-(2-(3-iodo-4-azidophenyl)ethyl)-4-(3-(trifluoromethyl)phenyl)piperazine is a complex chemical compound that belongs to the class of piperazine derivatives. It features a piperazine ring connected to a phenyl ring substituted with an iodine and an azide group, as well as another phenyl ring substituted with a trifluoromethyl group. The unique combination of these functional groups endows this compound with potential significance in medicinal chemistry and pharmaceutical applications.
Uses
Used in Scientific Research:
1-(2-(3-iodo-4-azidophenyl)ethyl)-4-(3-(trifluoromethyl)phenyl)piperazine is used as a molecular probe in scientific research for its unique structural features and potential interactions with biological systems.
Used in Drug Development:
In the pharmaceutical industry, 1-(2-(3-iodo-4-azidophenyl)ethyl)-4-(3-(trifluoromethyl)phenyl)piperazine is used as a lead compound for drug discovery due to its diverse pharmacological activities and the possibility of further chemical modifications to enhance its therapeutic potential.
Further research is necessary to fully understand the compound's potential and application in various fields, including its possible use in the development of new drugs targeting specific diseases or conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 118249-08-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,2,4 and 9 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 118249-08:
(8*1)+(7*1)+(6*8)+(5*2)+(4*4)+(3*9)+(2*0)+(1*8)=124
124 % 10 = 4
So 118249-08-4 is a valid CAS Registry Number.
InChI:InChI=1/C19H19F3IN5/c20-19(21,22)15-2-1-3-16(13-15)28-10-8-27(9-11-28)7-6-14-4-5-18(25-26-24)17(23)12-14/h1-5,12-13H,6-11H2
118249-08-4Relevant articles and documents
Preparation and biodistribution of -[125I]Iodo-4-aminophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperazine and -[125I]Iodo-4-azidophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperazine
Chumpradit,Kung,Billings,Guo,Wu,Shih
, p. 543 - 547 (2007/10/02)
The iodinated analogue of 1-[2-(4-aminophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperazine (PAPP), IPAPP (4), and the corresponding azido compound azido-IPAPP (5) were synthesized. The corresponding no-carrier-added 125I (T( 1/2 ) = 60 days, 35-60 keV) labeled compounds were also prepared. High specific binding was observed from in vitro binding studies using rat brain tissue preparation; K(i) = 20 and 17.5 nM against [3H]-5-HT. In vivo biodistribution studies in rats showed that azido-[125I]IPAPP passed through intact blood-brain barrier and localized in the brain. Ex vivo autoradiography of rat brain sections exhibited a diffuse uptake pattern, which may be due to specific and nonspecific binding. The results indicate that IPAPP and azido-IPAPP may not be suitable to image the serotonin receptor in the brain.