117811-20-8 Usage
Description
Dehydro Desloratadine is an impurity of Desloratadine (D290250), which is a second-generation antihistamine drug used for the treatment of allergic symptoms. It is characterized by its chemical structure, 8-chloro-11-(piperidin-4-ylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine.
Uses
Used in Pharmaceutical Industry:
Dehydro Desloratadine is used as an impurity in the development and validation of a stability-indicating ultra-performance liquid chromatography (UPLC) method for Desloratadine and its impurities in pharmaceutical dosage forms. This method ensures the quality, safety, and efficacy of Desloratadine-containing medications by accurately identifying and quantifying impurities, such as Dehydro Desloratadine, which can affect the drug's performance and safety profile.
Check Digit Verification of cas no
The CAS Registry Mumber 117811-20-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,8,1 and 1 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 117811-20:
(8*1)+(7*1)+(6*7)+(5*8)+(4*1)+(3*1)+(2*2)+(1*0)=108
108 % 10 = 8
So 117811-20-8 is a valid CAS Registry Number.
117811-20-8Relevant articles and documents
Bis-benzo or benzopyrido cyclohepta piperidene, piperidylidene and piperazine compounds, compositions and methods of use
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, (2008/06/13)
Bis-benzo or benzopyrido piperidene, piperidylidene and piperazine compounds of the formula: STR1 and pharmaceutically acceptable salts thereof are disclosed, wherein Z represents --(C(Ra)2)m --Y--(C(Ra)2)n -- or STR2 The compounds of Formula I possess anti-allergic and anti-inflammatory activity. Methods for preparing and using the compounds are also described.
Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies.
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, (2008/06/13)
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