117039-52-8

Basic information

• Product Name: 1-[4-(3-{4-[Bis-(4-fluoro-phenyl)-hydroxy-methyl]-piperidin-1-yl}-propoxy)-phenyl]-2,2-dimethyl-propan-1-one; compound with (E)-but-2-enedioic acid
• Synonyms: 1-[4-(3-{4-[Bis-(4-fluoro-phenyl)-hydroxy-methyl]-piperidin-1-yl}-propoxy)-phenyl]-2,2-dimethyl-propan-1-one; compound with (E)-but-2-enedioic acid
• CAS NO: 117039-52-8
• Molecular Weight: 637.721
• Mol File: 117039-52-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[4-(3-{4-[Bis-(4-fluoro-phenyl)-hydroxy-methyl]-piperidin-1-yl}-propoxy)-phenyl]-2,2-dimethyl-propan-1-one; compound with (E)-but-2-enedioic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(3-{4-[Bis-(4-fluoro-phenyl)-hydroxy-methyl]-piperidin-1-yl}-propoxy)-phenyl]-2,2-dimethyl-propan-1-one; compound with (E)-but-2-enedioic acid(117039-52-8)
• EPA Substance Registry System: 1-[4-(3-{4-[Bis-(4-fluoro-phenyl)-hydroxy-methyl]-piperidin-1-yl}-propoxy)-phenyl]-2,2-dimethyl-propan-1-one; compound with (E)-but-2-enedioic acid(117039-52-8)

Safety Data

• Hazardous Substances Data: 117039-52-8(Hazardous Substances Data)

Upstream product

• 60284-98-2 1,1-bis(4-fluorophenyl)-1-(4-piperidinyl)methanol 
• 110-17-8 (2E)-but-2-enedioic acid 
• 117022-49-8 1-[4-(3-Chloro-propoxy)-phenyl]-2,2-dimethyl-propan-1-one 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 24228-40-8 N-benzyl isonipecotic acid ethyl ester 
• 72569-10-9 1-(4-hydroxyphenyl)-2,2-dimethylpropan-1-one 

Relevant articles and documents

Synthesis and Antiallergy Activity of 4-(Diarylhydroxymethyl)-1-piperidines and Structurally Related Compounds

A series of 4-(diarylhydroxymethyl)-1-piperidines was synthesized and evaluated for antiallergy activity.Several analogues had potent activity in the passive foot anaphylaxis (PFA) assay, an IgE-mediated model useful in the detection of compounds possessing antiallergic activity.In particular 1--1-piperidinyl>propoxy>-3-methoxyphenyl>ethanone (1, AHR-5333) was more potent than oxatomide and terfenadine in this assay.