116761-04-7Relevant articles and documents
Reaction du methylure de dimethylsulfoxonium avec les ester α-fluoro α-ethyleniques
Elkik, Elias,Imbeaux-Oudotte, Michele
, p. 861 - 866 (2007/10/02)
The reaction of dimethylsulfoxonium methylide with α-fluoro α-ethylenic esters: R1-CH=CF-COOR' leads to the formation of β-keto-sulfoxonium ylides 3: R1CH=CF-CO=C-H-S+(O)(CH3)2.Reaction of ylides 3 with anhydrous HCl, at room temperature, provides β-keto γ,γ-fluoro-ethylenic sulfoxonium salts, whose decomposition, at high temperatures, leads to the formation of fluorinated chloromethyl-ketones: R1-CH=CF-CO-CH2Cl, which are not available by other methods.
