116477-53-3 Usage
Description
(+/-)17,18-DIHETE, also known as (±)17,18-dihydroxyeicosatetraenoic acid, is a type of dihydroxyeicosatetraenoic acid (DiHETE) derived from the oxidation of arachidonic acid. It is a biologically active metabolite that plays a role in mediating inflammation and immune responses in the body. (+/-)17,18-DIHETE is involved in various physiological processes, including the regulation of vascular tone, epithelial cell function, and platelet aggregation. (+/-)17,18-DIHETE has been studied for its potential therapeutic applications in the treatment of inflammatory and cardiovascular diseases. (+/-)17,18-DIHETE can be produced by various enzymes, and its levels are regulated by the body's natural metabolic pathways. Overall, (+/-)17,18-DIHETE is an important signaling molecule with diverse functions in the body's regulatory processes.
Uses
Used in Pharmaceutical Industry:
(+/-)17,18-DIHETE is used as a therapeutic agent for the treatment of inflammatory and cardiovascular diseases. Its role in mediating inflammation and immune responses makes it a promising candidate for managing conditions associated with these processes.
Used in Research Applications:
(+/-)17,18-DIHETE is used as a research tool to study the mechanisms of inflammation, immune responses, and other physiological processes. Understanding its role in these processes can help in the development of new therapeutic strategies and interventions for related diseases.
Used in Diagnostic Applications:
(+/-)17,18-DIHETE can be used as a biomarker to assess the presence or severity of inflammatory and cardiovascular conditions. Measuring its levels in biological samples can provide valuable information for diagnosis and monitoring of these diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 116477-53-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,6,4,7 and 7 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 116477-53:
(8*1)+(7*1)+(6*6)+(5*4)+(4*7)+(3*7)+(2*5)+(1*3)=133
133 % 10 = 3
So 116477-53-3 is a valid CAS Registry Number.
116477-53-3Relevant articles and documents
Selective terminal olefin oxidation of n-3 polyunsaturated fatty acids
Kato,Hirukawa,Namiki
, p. 1475 - 1478 (2007/10/02)
Through the action of N-bromosuccinimide in aqueous glyme, terminal double bond of n-3 fatty acids was selectively converted to the corresponding bromohydrin. This evidence suggests the tight conformation of the n-3 fatty acids in aqueous medium.
