116182-43-5

Basic information

• Product Name: 4H-Furo[2,3-c]pyranyl Mupirocin SodiuM IMpurity
• Synonyms: 4H-Furo[2,3-c]pyranyl Mupirocin SodiuM IMpurity;[2R-[2α(1S*,2S*,3S*),3aβ,6α(E),7β,7aα]]-9-[[4-[2-(1,3-Dihydroxy-2-Methylbutyl)hexahydro-7-hydroxy-4H-furo[3,2-c]pyran-6-yl]-3-Methyl-1-oxo-2-butenyl]oxy]nonanoic Acid MonosodiuM Salt
• CAS NO: 116182-43-5
• Molecular Formula: C26H43NaO9
• Molecular Weight: 647
• Product Categories: Chiral Reagents;Heterocycles;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Chiral Reagents, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 116182-43-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Methanol (Slightly), Water (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: 4H-Furo[2,3-c]pyranyl Mupirocin SodiuM IMpurity(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Furo[2,3-c]pyranyl Mupirocin SodiuM IMpurity(116182-43-5)
• EPA Substance Registry System: 4H-Furo[2,3-c]pyranyl Mupirocin SodiuM IMpurity(116182-43-5)

Safety Data

• Hazardous Substances Data: 116182-43-5(Hazardous Substances Data)

Usage

Description

4H-Furo[2,3-c]pyranyl Mupirocin SodiuM IMpurity is a rearrangement isomer of Mupirocin, a well-known antibiotic used for topical treatment of skin infections. It is prepared through an enzyme-catalyzed, selective deesterification process, which results in a unique chemical structure that differentiates it from the parent compound.

Uses

Used in Pharmaceutical Industry:
4H-Furo[2,3-c]pyranyl Mupirocin SodiuM IMpurity is used as a Mupirocin impurity for quality control and research purposes in the pharmaceutical industry. It helps in ensuring the purity and efficacy of Mupirocin-based medications by serving as a reference compound in analytical testing and method development.
Used in Research and Development:
4H-Furo[2,3-c]pyranyl Mupirocin SodiuM IMpurity is utilized as a research compound for studying the properties, mechanisms of action, and potential applications of Mupirocin and its derivatives. This impurity can provide valuable insights into the development of new antibiotics or improved formulations with enhanced efficacy and reduced side effects.
Used in Quality Control:
4H-Furo[2,3-c]pyranyl Mupirocin SodiuM IMpurity is employed as a reference material in the quality control processes of pharmaceutical companies. It aids in the accurate identification, quantification, and assessment of impurities in Mupirocin-containing products, ensuring their safety and compliance with regulatory standards.

Upstream product

• 62916-74-9 9-{(E)-4-[(2R,3aS,6S,7S,7aR)-2-((1S,2S,3S)-1,3-Dihydroxy-2-methyl-butyl)-7-hydroxy-hexahydro-furo[3,2-c]pyran-6-yl]-3-methyl-but-2-enoyloxy}-nonanoic acid methyl ester 

Relevant articles and documents

REGIOSELECTIVE ENZYMIC HYDROLYSIS IN THE ISOLATION OF ISOMERS OF MUPIROCIN

The rearrangement isomers of pseudomonic acid A have been prepared using an enzyme catalysed, selective de-esterification, and full NMR interpretations of the acid salts have been determined.