1158997-67-1Relevant articles and documents
Iron-catalyzed direct sulfenylation and selenylations of phenylpyrazoles: Synthesis of fipronil derivatives with disulfides promoted by a catalytic amount of iodine
Xu, Mei,Zhang, Xiao Hong,Zhong, Ping
experimental part, p. 3472 - 3481 (2012/09/22)
The direct thiolation of phenylpyrazole with disulfide using the FeBr 3/I2 complex as the catalyst in MeCN at 80 °C was reported. With the optimum conditions, several fipronil derivatives of 4-sulfenylpyrazole were synthesized by the reaction of 5-amino-1-[2,6-dichloro- 4-(trifluoromethyl)phenyl-lH-pyrazole-3-arbonitrile (1a) with disulfides (2) in moderate to good yields. The coupling reaction with diaryl diselane also occurred under similar conditions.