115818-54-7

Basic information

• Product Name: (E)-2,2-difluoro-3-hydroxy-1-phenyl-4-hexen-1-onen
• Synonyms: (E)-2,2-difluoro-3-hydroxy-1-phenyl-4-hexen-1-onen
• CAS NO: 115818-54-7
• Molecular Weight: 226.223
• Mol File: 115818-54-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-2,2-difluoro-3-hydroxy-1-phenyl-4-hexen-1-onen(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2,2-difluoro-3-hydroxy-1-phenyl-4-hexen-1-onen(115818-54-7)
• EPA Substance Registry System: (E)-2,2-difluoro-3-hydroxy-1-phenyl-4-hexen-1-onen(115818-54-7)

Safety Data

• Hazardous Substances Data: 115818-54-7(Hazardous Substances Data)

Upstream product

• 156544-69-3 ethyl (E)-2,2-difluoro-3-hydroxy-4-hexenoate 
• 865763-12-8 N-((E)-2,2-difluoro-3-hydroxy-4-hexenoyl)pyrrolidine 
• 591-51-5 phenyllithium 
• 123-73-9 trans-Crotonaldehyde 
• 384-67-8 2-chloro-2,2-difluoroacetophenone 

Downstream Products

• 128936-63-0 (E)-(1R,3S)-2,2-Difluoro-1-phenyl-hex-4-ene-1,3-diol 

Relevant articles and documents

Synthesis of stereocontrolled α,α-difluoro-β- hydroxycarbonyl materials

Synthesis and synthetic utilities of stereocontrolled α,α- difluoro-β-hydroxy-γ,δ-unsaturated carbonyl compounds via enzymatic resolution with lipase PS (Pseudomonas cepacia, Amano Pharmaceutical Co. Ltd.) or lipase MY (Candida rugosa, Meito Sangyo Co. Lt

ZINC-COPPER(I) CHLORIDE OR -SILVER(I) ACETATE PROMOTED ALDOL REACTION OF CHLORODIFLUOROMETHYL KETONES WITH CARBONYL COMPOUNDS. A GENERAL AND EFFECTIVE ROUTE TO α,α-DIFLUORO-β-HYDROXY KETONES

Chlorodifluoromethyl ketones efficiently underwent the aldol reaction with a variety of aldehydes or ketones in the presence of zinc, a catalytic amount of copper(I) chloride or silver(I) acetate, and molecular sieves to give the corresponding α,α-difluor