115256-13-8 Usage
Description
N-Methyl-N-(2-(4-aminophenoxy)ethyl)-2-(4-aminophenyl)ehtanamine, also known as 4-Amino-N-[2-(4-aminophenoxy)ethyl]-N-methylbenzeneethanamine, is a chemical compound that serves as an analogue of Dofetilide (D525700). It is characterized by its pale yellow to yellow powder appearance and is primarily recognized for its role as a potassium channel blocker.
Uses
Used in Pharmaceutical Industry:
N-Methyl-N-(2-(4-aminophenoxy)ethyl)-2-(4-aminophenyl)ehtanamine is used as a potassium channel blocker for various medical applications. As an analogue of Dofetilide, it plays a crucial role in the treatment of certain cardiovascular conditions by regulating the flow of potassium ions through cell membranes, which can help stabilize the electrical activity of the heart.
Used in Research and Development:
In addition to its pharmaceutical applications, N-Methyl-N-(2-(4-aminophenoxy)ethyl)-2-(4-aminophenyl)ehtanamine is also utilized in research and development settings. Scientists and researchers employ this compound to study the effects of potassium channel blockers on cellular processes and to develop new therapeutic strategies for a range of medical conditions.
Used in Drug Design and Synthesis:
The compound is also used in drug design and synthesis, where it serves as a starting point or a key intermediate for the development of novel potassium channel blockers with improved pharmacological properties. These new compounds may offer better efficacy, reduced side effects, or targeted delivery to specific tissues or organs.
Check Digit Verification of cas no
The CAS Registry Mumber 115256-13-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,2,5 and 6 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 115256-13:
(8*1)+(7*1)+(6*5)+(5*2)+(4*5)+(3*6)+(2*1)+(1*3)=98
98 % 10 = 8
So 115256-13-8 is a valid CAS Registry Number.
115256-13-8Relevant articles and documents
A preparing method of a dofetilide intermediate
-
Paragraph 0045; 0073-0074, (2018/07/06)
A preparing method of a dofetilide intermediate and analogues thereof is disclosed. The method includes steps of dissolving a compound of the formula (I) into a reaction solvent, converting -NO2 of the compound of the formula (I) into -NH2 through hydroge
Selective class III antiarrhythmic agents. 1. Bis(arylalkyl)amines
Cross,Arrowsmith,Thomas,Gwilt,Burges,Higgins
, p. 1151 - 1155 (2007/10/02)
A series of bis(arylalkyl)amines is described and their effects on prolonging effective refractory period in isolated cardiac tissue listed. Most compounds prolonged the cardiac action potential without significantly altering the maximum rate of depolarization and may be defined as selective class III antiarrhythmic agents. It was found that a particularly advantageous structural feature was to have a methanesulfonamido moiety on both of the aryl rings. Thus, compound 16 [1-(4-methanesulfonamidophenoxy)-2-[N-(4-methanesulfonamidophenethyl)- N-methylamine]ethane] was selected for further investigations. The compound is highly potent and selective class III agent which acts by blockade of cardiac potassium channels.
