114362-20-8 Usage
Description
2-Tert-butylpyrimidin-4-amine is an organic compound characterized by a pyrimidine ring with a tert-butyl group at the 2nd position and an amine functional group at the 4th position. It is a versatile intermediate in the synthesis of various pyrimidine-based compounds.
Uses
Used in Pharmaceutical Industry:
2-Tert-butylpyrimidin-4-amine is used as a reactant in the preparation of pyrimidines via cyclization, ring transformation, aromatization, and substituent modification. These pyrimidine-based compounds are valuable for the development of pharmaceuticals, particularly as antiviral, anticancer, and antimalarial agents, due to their ability to interact with key biological targets and inhibit essential cellular processes in disease-causing organisms.
Used in Chemical Research:
In the field of chemical research, 2-Tert-butylpyrimidin-4-amine serves as a key building block for the synthesis of novel pyrimidine derivatives with potential applications in material science, supramolecular chemistry, and as ligands in coordination chemistry. Its reactivity and structural features make it an attractive candidate for exploring new reactions and developing innovative synthetic methodologies.
Check Digit Verification of cas no
The CAS Registry Mumber 114362-20-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,3,6 and 2 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 114362-20:
(8*1)+(7*1)+(6*4)+(5*3)+(4*6)+(3*2)+(2*2)+(1*0)=88
88 % 10 = 8
So 114362-20-8 is a valid CAS Registry Number.
114362-20-8Relevant articles and documents
11B-HSD1 inhibitors for the treatment of diabetes
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Page/Page column 11, (2008/06/13)
Compounds of the formula (I): as well as pharmaceutically acceptable salts and esters thereof, wherein R1 to R5 have the significance given in claim 1 can be used in the form of pharmaceutical compositions.