1141886-66-9 Usage
Description
(3-exo)-8-Methyl-8-azabicyclo[3.2.1]octane-3-thiol hydrochloride is an organic compound with a unique bicyclic structure and a thiol functional group. It is characterized by its exo position, which refers to the orientation of the thiol group outside the ring system. (3-exo)-8-Methyl-8-azabicyclo[3.2.1]octane-3-thiol hydrochloride is a derivative of azabicycloalkane, which is a type of nitrogen-containing bicyclic compound. The presence of the thiol group (-SH) in its structure makes it a potential candidate for various chemical reactions and applications.
Uses
Used in Pharmaceutical Industry:
(3-exo)-8-Methyl-8-azabicyclo[3.2.1]octane-3-thiol hydrochloride is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and functional groups make it a valuable building block for the development of new drugs with specific therapeutic properties.
Used in the Synthesis of Retapamulin (R279008):
(3-exo)-8-Methyl-8-azabicyclo[3.2.1]octane-3-thiol hydrochloride is used as a key intermediate in the synthesis of Retapamulin (R279008), an antibacterial agent. Retapamulin is a valuable alternative to the more commonly known Penicillin (P223505) and is used to treat bacterial infections, particularly those caused by methicillin-resistant Staphylococcus aureus (MRSA).
Check Digit Verification of cas no
The CAS Registry Mumber 1141886-66-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,4,1,8,8 and 6 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1141886-66:
(9*1)+(8*1)+(7*4)+(6*1)+(5*8)+(4*8)+(3*6)+(2*6)+(1*6)=159
159 % 10 = 9
So 1141886-66-9 is a valid CAS Registry Number.
1141886-66-9Relevant articles and documents
NOVEL PROCESS, SALTS, COMPOSITIONS AND USE
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Page/Page column 34, (2008/06/13)
The present invention provides a novel process for preparing pleuromutilin derivatives, novel salts of mutilin 14-(exo-8-methyl-8-azabicyclo[3.2.l]oct-3-ylsulfanyl)-acetate or solvates thereof, novel pharmaceutical compositions or formulations for topical administration comprising mutilin 14-(exo-8- methyl-8-azabicyclo[3.2.1]oct-3-ylsulfanyl)-acetate or a pharmaceutically acceptable salt or solvate thereof and their use in medical therapy, particularly antibacterial therapy.
