1122552-37-7

Basic information

• Product Name: 2,5-bis[3-(p-bromophenyl)-1,2,4-triazolo[3,4-b]-[1,3,4]thiadiazol-6-yl]thiophene
• CAS NO: 1122552-37-7
• Molecular Weight: 642.381
• Mol File: 1122552-37-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,5-bis[3-(p-bromophenyl)-1,2,4-triazolo[3,4-b]-[1,3,4]thiadiazol-6-yl]thiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-bis[3-(p-bromophenyl)-1,2,4-triazolo[3,4-b]-[1,3,4]thiadiazol-6-yl]thiophene(1122552-37-7)
• EPA Substance Registry System: 2,5-bis[3-(p-bromophenyl)-1,2,4-triazolo[3,4-b]-[1,3,4]thiadiazol-6-yl]thiophene(1122552-37-7)

Safety Data

• Hazardous Substances Data: 1122552-37-7(Hazardous Substances Data)

Upstream product

• 4282-31-9 Thiophene-2,5-dicarboxylic acid 
• 85106-58-7 4?amino?5?(4?bromophenyl)?4H?1,2,4?triazole?3?thiol 

Relevant articles and documents

The synthesis and antibacterial activities of 2,5-bis[(3-aryl)-1,2,4- triazolo[3,4-b]-[1,3,4] thiadiazole-6-yl]thiophenes

2,5-bis[(3-aryl)-1,2,4-triazolo[3,4-b]-[1,3,4]thiadiazole-6-yl]thiophenes 2 were synthesized in high yields by cyclization of 3-aryl 4-amino-5-mercapto-1, 2,4-triazole 1 with thiophene-2,5-dicarboxylic acid in the presence of POCl3 and tetrabutylammonium iodide as catalyst. The preliminary antibacterial tests showed that most of them were effective against S. aureus, E. coli and B. subtilis. Compounds 2b, 2c, 2d, 2m, 2n, and 2o exhibited promising antibacterial activity. Compounds 2 were screened for their fungicidal activities against Gibberella zeae, Cerospora beticola sacc, Physalospora piricola and Pellicularia sasakii. Compounds 2b, 2c, and 2d showed a high degree of inhibition against Cerospora beticola sacc. Copyright Taylor & Francis Group, LLC.