112-66-3Relevant articles and documents
CARBONYLATION DES COMPLEXES μ-ALKYLIDENIQUES: MISE EN EVIDENCE D'UN COMPOSE MINEUR PROVENANT D'UNE DOUBLE INSERTION DE CO
Navarre, D.,Rose-Munch, F.,Rudler, H.
, p. C15 - C18 (1985)
While the μ-alkylidenetungsten complex, (CO)9W2CHCH=C(CH3)2 gives the expected ester resulting from CO insertion-solvolysis reactions, the μ-alkylideneiron complex (CO)8Fe2CH2 gives, as well as the expected ester, a malonate formed by double carbonylation of the bridging carbon atom.
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Laughlin,R.G.
, p. 1005 - 1011 (1962)
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Dodecyl sodium sulfoacetate synthesis process
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Paragraph 0034-0036, (2019/02/13)
The invention relates to the technical field of chemical synthesis processes, particularly to a dodecyl sodium sulfoacetate synthesis process. According to the present invention, by adjusting the feeding weight ratio, optimizing the reaction conditions and improving the dodecyl sodium sulfoacetate synthesis route, the requirements on the compound reaction conditions are low, the control of the reaction is simple, and the yield is increased while the quality of the intermediate product is greatly improved so as to reduce the process control difficulty in the dodecyl sodium sulfoacetate production process and improve the quality and the qualification rate of dodecyl sodium sulfoacetate; and various steps of the preparation process are simple, the solvents and the process conditions are safeand easy to perform, the environmental protection production is achieved, and the method has broad application prospects.
A General Catalytic Method for Highly Cost- and Atom-Efficient Nucleophilic Substitutions
Huy, Peter H.,Filbrich, Isabel
supporting information, p. 7410 - 7416 (2018/04/30)
A general formamide-catalyzed protocol for the efficient transformation of alcohols into alkyl chlorides, which is promoted by substoichiometric amounts (down to 34 mol %) of inexpensive trichlorotriazine (TCT), is introduced. This is the first example of a TCT-mediated dihydroxychlorination of an OH-containing substrate (e.g., alcohols and carboxylic acids) in which all three chlorine atoms of TCT are transferred to the starting material. The consequently enhanced atom economy facilitates a significantly improved waste balance (E-factors down to 4), cost efficiency, and scalability (>50 g). Furthermore, the current procedure is distinguished by high levels of functional-group compatibility and stereoselectivity, as only weakly acidic cyanuric acid is released as exclusive byproduct. Finally, a one-pot protocol for the preparation of amines, azides, ethers, and sulfides enabled the synthesis of the drug rivastigmine with twofold SN2 inversion, which demonstrates the high practical value of the presented method.