1116-98-9Relevant articles and documents
Studies in isoxazole chemistry. 5. N-alkylation and N-acylation of 5-amino-3-(5-nitro-2-furyl)isoxazoles.
Micetich,Raap,Chin
, p. 856 - 860 (1971)
-
Synthesis, photo-electrochemical properties and dye-sensitized solar cell performance of d-π-A structured porphyrins
Zhang, Hongxing,Zheng, Xiuwen,Li, Haiying,Jin, Bin,Wang, Chengyun,Shen, Yongjia,Hua, Jianli
, p. 58 - 64 (2013)
Two new dye sensitizers 5-(N,N-4-(diphenylamino)phenyl)-10-(4-(tert-butyl- 2-cyanoacrylate)phenyl)porphyrin (TP) and 5-(N, N-4-(bis(4-butylphenyl) amino) phenyl)-10-(4-(tert-butyl-2-cyanoacrylate)phenyl)porphyrin (BUTP) with cyanoacrylic acid as electron acceptor were synthesized and researched. BUTP has strong absorption in a wide range of 300-726 nm. DSSCs sensitized by BUTP displayed a power conversion efficiency (η) 5.33%, JSC 12.21 mA cm-2, Voc 0.68 V, FF 0.65, under the illumination of AM 1.5 G. Spectral properties, electrochemical properties, photovoltaic and electrochemical impedance properties of TP and BUTP were also investigated. Considering its simple synthesis, both TP and BUTP were qualified sensitizers for DSSCs.
Synthesis method of tert-butyl cyanoacetate
-
Paragraph 0021-0035, (2021/04/14)
The invention belongs to the technical field of organic chemistry, and particularly relates to a synthesis method of tert-butyl cyanoacetate. Cyanoacetic acid and isobutene are subjected to a catalytic esterification reaction in an organic solvent in the presence of Lewis acid to obtain tert-butyl cyanoacetate. The method provided by the invention has the advantages of cheap and easily available raw materials, mild reaction conditions, simple operation, simple post-treatment, low cost, high product yield and high product purity, and is easy for industrial production.
Development of the First Two-Pore Domain Potassium Channel TWIK-Related K+ Channel 1-Selective Agonist Possessing in Vivo Antinociceptive Activity
Vivier, Delphine,Soussia, Ismail Ben,Rodrigues, Nuno,Lolignier, Stéphane,Devilliers, Ma?ly,Chatelain, Franck C.,Prival, Laetitia,Chapuy, Eric,Bourdier, Geoffrey,Bennis, Khalil,Lesage, Florian,Eschalier, Alain,Busserolles, Jér?me,Ducki, Sylvie
, p. 1076 - 1088 (2017/02/19)
The TWIK-related K+ channel, TREK-1, has recently emerged as an attractive therapeutic target for the development of a novel class of analgesic drugs, suggesting that activation of TREK-1 could result in pain inhibition. Here, we report the synthesis of a series of substituted acrylic acids (1-54) based on our previous work with caffeate esters. The analogues were evaluated for their ability to modulate TREK-1 channel by electrophysiology and for their in vivo antinociceptive activity (acetic acid-induced writhing and hot plate assays), leading to the identification of a series of novel molecules able to activate TREK-1 and displaying potent antinociceptive activity in vivo. Furyl analogue 36 is the most promising of the series.