110972-51-5

Basic information

• Product Name: potassium (R)-3-hydroxybutyrate
• CAS NO: 110972-51-5
• Molecular Weight: 142.196
• Mol File: 110972-51-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: potassium (R)-3-hydroxybutyrate(CAS DataBase Reference)
• NIST Chemistry Reference: potassium (R)-3-hydroxybutyrate(110972-51-5)
• EPA Substance Registry System: potassium (R)-3-hydroxybutyrate(110972-51-5)

Safety Data

• Hazardous Substances Data: 110972-51-5(Hazardous Substances Data)

Usage

General Description

Potassium (R)-3-hydroxybutyrate is a chemical compound that belongs to the class of ketone bodies, which are produced by the liver during periods of low food intake. It is a salt form of R-3-hydroxybutyric acid, a ketone body that serves as an alternative energy source for the body, particularly the brain, when glucose is not readily available. Potassium (R)-3-hydroxybutyrate is used as a dietary supplement and may be taken by individuals following a ketogenic diet to help increase blood ketone levels and support ketosis, a metabolic state in which the body uses fat for fuel instead of carbohydrates. It has also been studied for its potential therapeutic effects in conditions such as epilepsy, neurodegenerative diseases, and metabolic disorders.

Upstream product

• 24915-95-5 Ethyl (R)-3-hydroxybutanoate 

Relevant articles and documents

Synthesis process of (R)-3-hydroxybutyric acid and salts thereof

The invention discloses a synthesis process for preparing (R)-3-hydroxybutyric acid and sodium salt, potassium salt, magnesium salt and calcium salt thereof. The process includes steps: adding 3-oxobutanoate and a ruthenium complex catalyst into organic solvent according to a mole ratio of 1:0.0005-0.005, and reacting at 20-80 DEG C for 12-24h under a hydrogen pressure of 1-20bar to obtain (R)-3-hydroxybutyrate; dissolving (R)-3-hydroxybutyrate into water, and subjecting to reaction with sodium hydroxide, potassium hydroxide or calcium hydroxide for 2-12h at a low temperature to obtain sodium salt, potassium salt, magnesium salt and calcium salt of (R)-3-hydroxybutyric acid; subjecting water solution of (R)-3-sodium hydroxybutyrate to 732 cation exchange resin treatment to remove sodium ions to obtain (R)-3-hydroxybutyric acid; subjecting (R)-3-hydroxybutyric acid to reaction with magnesium hydroxide to obtain (R)-3-magnesium hydroxybutyrate. Ee values of (R)-3-hydroxybutyric acid and sodium salt, potassium salt, magnesium salt and calcium salt thereof reach 90% or above. The method has advantages of low environment pollution, low cost and easiness in aftertreatment.