110952-70-0

Basic information

• Product Name: (+/-)-COTININE-D3
• Synonyms: DL-COTININE-D3 (N-METHYL-D3);(+/-)-COTININE-D3;COTININE-D3 (N-METHYL-D3);1-METHYL-D3]-5-[3-PYRIDINYL]-2-PYRROLIDINONE;COTININE-METHYL-D3, 99 ATOM % D;(-1-(Methyl-d3)-5-(2-pyridinyl)-2-pyrrolidinone;(±)-cotinine-d3(methyl-d3);rac Cotinine-d3
• CAS NO: 110952-70-0
• Molecular Formula: C10H9D3N2O
• Molecular Weight: 179.23
• Product Categories: Isotope Labeled Compounds;Metabolites & Impurities;Nicotine Derivatives;Heterocycles;Isotope Labelled Compounds
• Mol File: 110952-70-0.mol
• Article Data: 0

Chemical Properties

• Melting Point: 40-42 °C(lit.)
• Boiling Point: 250 °C150 mm Hg(lit.)
• Flash Point: 9℃
• Appearance: /
• Density: 1.166g/cm³
• Vapor Pressure: 0.000421mmHg at 25°C
• Refractive Index: 1.555
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• Stability: Moisture, Temperature Sensitive - Seal Tightly, Store in Freezer, Hygroscopic
• CAS DataBase Reference: (+/-)-COTININE-D3(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-COTININE-D3(110952-70-0)
• EPA Substance Registry System: (+/-)-COTININE-D3(110952-70-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26
• RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
• WGK Germany: 3
• Hazardous Substances Data: 110952-70-0(Hazardous Substances Data)

Usage

Description

(+/-)-COTININE-D3 is a stable-labeled internal standard of cotinine, an alkaloid found in tobacco and a major urinary metabolite of nicotine. It is used for the quantitation of cotinine levels in various biological samples such as urine, blood, and saliva. (+/-)-COTININE-D3 is particularly useful in nicotine testing, as well as in clinical and diagnostic testing of nicotine biomarkers. It is a white crystalline solid and is also recognized as a carcinogen.

Uses

Used in Pharmaceutical and Diagnostic Industry:
(+/-)-COTININE-D3 is used as a stable internal standard for the accurate quantitation of cotinine levels in biological samples. This application is crucial for nicotine testing and the clinical and diagnostic assessment of nicotine biomarkers, which are essential in understanding and managing nicotine addiction and its related health issues.
Used in Research and Development:
In the research and development sector, (+/-)-COTININE-D3 serves as a valuable tool for studying the metabolism and pharmacokinetics of nicotine. This helps in the development of new treatments and therapies for nicotine addiction and related health conditions.
Used in Toxicology and Forensic Analysis:
(+/-)-COTININE-D3 is employed as a reference compound in toxicology and forensic analysis to determine the presence and concentration of cotinine in biological samples. This information can be used in cases where nicotine exposure or poisoning is suspected, aiding in the investigation and prosecution of such incidents.
Used in Public Health and Epidemiological Studies:
As a major metabolite of nicotine, (+/-)-COTININE-D3 is used in public health and epidemiological studies to assess the prevalence of tobacco use and exposure to secondhand smoke. This helps in understanding the impact of tobacco use on public health and informs policy decisions related to tobacco control and prevention strategies.

InChI:InChI=1/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/i1D3