110729-51-6Relevant articles and documents
Selective sodium channel regulator as well as preparation and application thereof
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Paragraph 0094-0095; 0111-0114, (2021/02/10)
The invention provides a compound serving as a selective sodium channel regulator and a synthesis and use method, and particularly provides a compound shown as a formula (I), a preparation method of the compound and application of the compound serving as the selective sodium channel regulator. The compounds exhibit excellent activity as a regulator of sodium channels.
Carbazole and Carboline Compounds for Use in the Diagnosis, Treatment, Alleviation or Prevention of Disorders Associated with Amyloid or Amyloid-Like Proteins
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Paragraph 0816; 0817; 0818; 0819; 0820, (2017/01/23)
The present invention relates to novel compounds that can be employed in the diagnosis, treatment, alleviation or prevention of a group of disorders and abnormalities associated with amyloid proteins and amyloid-like proteins, such as Alzheimer's disease. Precursors for the preparation of the compounds according to the present invention are also provided.
Pyrimidine derivative, preparation method and applications thereof
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Paragraph 0079-0081, (2016/11/17)
The present invention provides a pyrimidine derivative represented by a formula (I) or a pharmaceutically acceptable salt thereof, a preparation method and applications thereof, wherein the pyrimidine derivative represented by a formula (I), or pharmaceutically acceptable salt thereof has JAK kinase inhibition activity, particularly provides selective and high inhibition activity on JAK3 kinase, can be used for preparation of a JAK3 kinase inhibitor, and can be used for preparation of drugs for prevention or treatment of diseases associated with abnormal JAK3 kinase activity so as to prevent or treat diseases associated with abnormal JAK3 kinase activity. The formula (I) is defined in the specification.