1098-60-8 Usage
Description
Triflupromazine hydrochloride, also known as 10-[3-(dimethylamino)propyl]-2-(trifluoromethyl)phenothiazine monohydrochloride (Vesprin), is a phenothiazine with diverse biological activities. It exhibits a higher potency as an antipsychotic, with greater extrapyramidal symptoms (EPS) but lower sedative and hypotensive effects compared to chlorpromazine. Triflupromazine binds to muscarinic receptors, inhibits serotonin uptake, and demonstrates activity against various pathogens, including T. cruzi, S. aureus, shigellae, and vibrios. It was previously used as an antipsychotic under the brand name Vesprin by Bristol-Myers Squibb.
Uses
Used in Pharmaceutical Industry:
Triflupromazine hydrochloride is used as an analgesic, anti-inflammatory, and antipyretic agent for its ability to alleviate pain, reduce inflammation, and lower fever. Its action as a COX-II inhibitor contributes to these effects.
Used in Psychiatry:
Triflupromazine hydrochloride is used as an antipsychotic agent for the treatment of various psychiatric disorders due to its higher potency and lower sedative and hypotensive effects compared to other antipsychotics.
Used in Infectious Disease Treatment:
Triflupromazine hydrochloride is used as an antimicrobial agent for its in vitro activity against S. aureus, shigellae, and vibrios, as well as its protective effects against S. typhimurium infection in mice.
Therapeutic Function
Tranquilizer
Check Digit Verification of cas no
The CAS Registry Mumber 1098-60-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,9 and 8 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1098-60:
(6*1)+(5*0)+(4*9)+(3*8)+(2*6)+(1*0)=78
78 % 10 = 8
So 1098-60-8 is a valid CAS Registry Number.
InChI:InChI=1/C18H19F3N2S.ClH/c1-22(2)10-5-11-23-14-6-3-4-7-16(14)24-17-9-8-13(12-15(17)23)18(19,20)21;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H
