109434-23-3

Basic information

• Product Name: FMOC-CYS(TBU)-OPFP
• Synonyms: FMOC-S-T-BUTYL-L-CYSTEINE PENTAFLUOROPHENYL ESTER;FMOC-CYS(TBU)-OPFP;FMOC-CYSTEINE(TBU)-OPFP;FMOC-CYS(BUT)-OPFP;N-ALPHA-FMOC-S-T-BUTYL-L-CYSTEINE PENTAFLUOROPHENYL ESTER;N-ALPHA-FMOC-S-TERT-BUTYL-L-CYSTEINE PENTAFLUOROPHENYL ESTER;N(alpha)-fmoc-S-T-butyl-L-cysteine pentafluorophe.ester;NALPHA-9-Fluorenylmethoxycarbonyl-S-tert-butyl-L-cysteine pentafluorophenyl
• CAS NO: 109434-23-3
• Molecular Formula: C₂₈H₂₄F₅NO₄S
• Molecular Weight: 565.55
• Product Categories: Amino Acids
• Mol File: 109434-23-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: FMOC-CYS(TBU)-OPFP(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-CYS(TBU)-OPFP(109434-23-3)
• EPA Substance Registry System: FMOC-CYS(TBU)-OPFP(109434-23-3)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 10
• Hazardous Substances Data: 109434-23-3(Hazardous Substances Data)

Usage

Description

FMOC-CYS(TBU)-OPFP, also known as 9-fluorenylmethoxycarbonyl-L-cysteine(2,2,2-trifluoro-1-(1H-tetrazol-5-yl)ethyl)ester, is a chemical compound that serves as a building block in the synthesis of peptides and proteins. It is characterized by the presence of a 9-fluorenylmethoxycarbonyl (Fmoc) group, which is a protecting group for the amino group, and a 2,2,2-trifluoro-1-(1H-tetrazol-5-yl)ethyl (OPfp) ester, which is a side chain protecting group for the thiol group of the cysteine residue. FMOC-CYS(TBU)-OPFP is a valuable reagent in the field of organic synthesis and peptide chemistry.

Uses

Used in Peptide Synthesis:
FMOC-CYS(TBU)-OPFP is used as a reactant in the preparation of heterotrimeric collagen peptides. It plays a crucial role in the synthesis of collagen-like structures, which are essential components of the extracellular matrix in various tissues. The Fmoc group protects the amino group during the synthesis process, while the OPfp group protects the thiol group, allowing for the controlled formation of disulfide bonds that are critical for the stability and function of collagen peptides.
Used in Pharmaceutical Industry:
FMOC-CYS(TBU)-OPFP is used as a building block for the synthesis of therapeutic peptides and proteins in the pharmaceutical industry. Its ability to protect the amino and thiol groups during synthesis allows for the production of complex peptide structures with specific biological activities. These synthesized peptides and proteins can be used as drugs or drug candidates for the treatment of various diseases and conditions.
Used in Research and Development:
FMOC-CYS(TBU)-OPFP is used as a research tool in the development of new synthetic methods and strategies for peptide synthesis. Its unique protecting groups enable the exploration of novel approaches to the assembly of peptide chains and the formation of disulfide bonds, which are essential for the proper folding and function of many biologically active peptides and proteins.

Downstream Products

• 143038-42-0 Fmoc-Cys(StBu)-Thr(tBu)-OH