108132-06-5

Basic information

• Product Name: 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4,5-trimethoxyphenyl)-
• CAS NO: 108132-06-5
• Molecular Formula: C18H18O6
• Molecular Weight: 330.337
• Mol File: 108132-06-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4,5-trimethoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4,5-trimethoxyphenyl)-(108132-06-5)
• EPA Substance Registry System: 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4,5-trimethoxyphenyl)-(108132-06-5)

Safety Data

• Hazardous Substances Data: 108132-06-5(Hazardous Substances Data)

Upstream product

• 89-84-9 2',4'-dihydroxy-4-acetophenone 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 2079-52-9 1-(2,4-bis(allyloxy)phenyl)ethanone 
• 111797-31-0 (E)-1-(2-hydroxy-4-(methoxymethoxy)phenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one 
• 65490-08-6 2-hydroxy-4-(methoxymethoxy)acetophenone 
• 25015-92-3 2-chloro-1-(2,4-dihydroxyphenyl)ethanone 
• 108-46-3 recorcinol 
• 6515-05-5 2',4'-bis(methoxymethoxy)acetophenone 

Downstream Products

• 2679-65-4 (E)-1-(2,4-dihydroxyphenyl)-3-(3,4,5-trihydroxyphenyl)prop-2-en-1-one 
• 66922-84-7 7-hydroxy-2-(3,4,5-trimethoxyphenyl)-4H-chromen-4-one 

Relevant articles and documents

Design, synthesis and biological evaluation of 3′,4′,5′-trimethoxy flavonoid benzimidazole derivatives as potential anti-tumor agents

A series of 3′,4′,5′-trimethoxy flavonoids with benzimidazole linked by different chain alkanes have been designed and synthesized. The potential activity of these compounds as anti-tumor agents was evaluated by cytotoxicity assay in MGC-803 (human gastri

Flavonoid glycosides with a triazole moiety for marine antifouling applications: Synthesis and biological activity evaluation

Over the last decades, antifouling coatings containing biocidal compounds as active ingre-dients were used to prevent biofouling, and eco-friendly alternatives are needed. Previous research from our group showed that polymethoxylated chalcones and glycosy

Synthesis and biological evaluation of isoliquiritigenin derivatives as a neuroprotective agent against glutamate mediated neurotoxicity in HT22 cells

Glutamate-induced neurotoxicity is characterized by cellular Ca2+ uptake, which is upstream of reactive oxygen species (ROS)-induced apoptosis signaling and MAPKs activation. In the present study, we synthesized isoliquiritigenin analogs with electron-donating and electron-withdrawing functional groups. These analogs were evaluated for neuroprotective effect against glutamate-induced neurotoxicity in HT22 cells. Among these analogs, compound BS11 was selected as a potent neuroprotective agent. Cellular Ca2+ concentration, ROS level, MAPKs activation and AIF translocation to the nucleus were increased upon treatment with 5 mM glutamate. In contrast, we identified that compound BS11 reduced the cellular Ca2+ concentration and ROS level upon glutamate exposure. Western blot analysis showed that MAPK activation was decreased by treatment with compound BS11. We further identified that cotreatment of compound BS11 and glutamate inhibited translocation of AIF to the nucleus.