1073-21-8

Basic information

• Product Name: 3-Amino-2,4-dimethylpyridine
• Synonyms: 3-AMINO-2,4-DIMETHYLPYRIDINE;3-Amino-2,4-dimethylpyridine 97%;2,4-dimethylpyridin-3-amine;2,4-diMethyl-3-PyridinaMine;PyriMido[1,2-b]pyridazin-2-one;2,4-Dimethylpyridin-3-amine, 3-Amino-2,4-lutidine;3-Amino-2,4-dimethylpyridine97%
• CAS NO: 1073-21-8
• Molecular Formula: C₇H₁₀N₂
• Molecular Weight: 122.17
• Product Categories: Heterocyclic Compound;Amines;Pyridines
• Mol File: 1073-21-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 53 °C
• Boiling Point: 255.708 °C at 760 mmHg
• Flash Point: 132.153 °C
• Appearance: Pale brown/Crystalline Powder
• Density: 1.04 g/cm³
• Vapor Pressure: 0.016mmHg at 25°C
• Refractive Index: 1.564
• Storage Temp.: 2-8°C
• PKA: 7.54±0.18(Predicted)
• CAS DataBase Reference: 3-Amino-2,4-dimethylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-2,4-dimethylpyridine(1073-21-8)
• EPA Substance Registry System: 3-Amino-2,4-dimethylpyridine(1073-21-8)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• HazardClass: 6.1
• Hazardous Substances Data: 1073-21-8(Hazardous Substances Data)

Usage

Description

3-Amino-2,4-dimethylpyridine is an organic compound characterized by its pyridine ring structure with an amino group at the 3rd position and two methyl groups at the 2nd and 4th positions. It is a versatile building block in organic synthesis and has been found to be particularly useful in the development of various pharmaceutical compounds.

Uses

Used in Pharmaceutical Synthesis:
3-Amino-2,4-dimethylpyridine is used as a key intermediate in the synthesis of diazepines and their derivatives, which are known for their diverse range of biological activities, including sedative, hypnotic, and anxiolytic effects. The compound plays a crucial role in the development of new drugs targeting the central nervous system.
Used in Chemical Research:
In addition to its pharmaceutical applications, 3-Amino-2,4-dimethylpyridine is also utilized as a reagent in various chemical research studies. Its unique structure allows for the exploration of novel chemical reactions and the synthesis of new compounds with potential applications in various fields, such as materials science, agrochemistry, and environmental science.

InChI:InChI=1/C7H10N2/c1-5-3-4-9-6(2)7(5)8/h3-4H,8H2,1-2H3

Upstream product

• 22934-24-3 3-nitro-6-hydroxy-2,4-dimethylpyridine 
• 108-47-4 2,4-lutidine 
• 55314-30-2 2,4-dimethylnicotinic acid 
• 1074-76-6 2,4-dimethyl-3-nitropyridine 
• 89793-08-8 6-chloro-2,4-dimethyl-3-nitropyridine 

Downstream Products

• 27296-76-0 2,4-dimethyl-pyridin-3-ol 
• 860411-35-4 7-methyl-3H-pyrazolo[3,4-c]pyridine 
• 1417332-55-8 1-(4-Methoxy-phenyl)-3-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (2,4-dimethyl-pyridin-3-yl)-amide 
• 1417331-93-1 1-(4-Methoxy-phenyl)-3,6-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (2,4-dimethyl-pyridin-3-yl)-amide 
• 1345828-49-0 1-(4-fluoro-phenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid (2,4-dimethyl-pyridin-3-yl)-amide 
• 897733-12-9 6-bromo-2,4-dimethyl-pyridin-3-amine 
• 143509-33-5 2,4-dimethyl-3-hydroxypyridine N-oxide 
• 1421251-56-0 2-(2,6-diethylphenyl)-6-(2,4-dimethylpyridin-3-yl)-4-methyl-5,6,7,8-tetrahydro(5,5-²H₂)-1,6-naphthyridine 
• 1421254-08-1 2-(2,6-diethylphenyl)-6-(2,4-dimethylpyridin-3-yl)-4-methyl-7,8-dihydro-1,6-naphthyridin-5(6H)-one 
• 1421254-07-0 2-(2,6-diethylphenyl)-6-(2,4-dimethylpyridin-3-yl)-4-methyl-1,6-naphthyridin-5(6H)-one 

Relevant articles and documents

Synthesis and Antitumor Activity of 3- and 5-Hydroxy-4-methylpyridibe-2-carboxaldehyde Thiosemicarbazones

To develop an α-(N)-heterocyclic carboxaldehyde thiosemicarbazone with clinical utility as an anticancer agent, two analogues, 3-hydroxy-4-methylpyridine-2-carboxaldehyde thiosemicarbazone (3-HMP) and 5-hydroxy-4-methylpyridine-2-carboxaldehyde thiosemicarbazone (5-HMP), of 5-hydroxypyridine-2-carboxaldehyde thiosemicarbazone (5-HP) have been designed and synthesized by two different methods. 3-HMP and 5-HMP both showed better antitumor activity than their respective parent compounds, 3-hydroxypyridine-2-carboxaldehyde thiosemicarbazone and 5-HP, in mice bearing the L1210 leukemia.

Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto

The present invention relates to certain substituted pyridinyl and pyrimidinyl derivatives of Fomula (Ia) that are modulators of metabolism. Accordingly, compounds of the present invention are useful in the treatment of metabolic-related disorders and com

THE EFFECT OF VICINAL METHYL GROUPS ON THE REDUCTION OF AROMATIC NITRO COMPOUNDS WITH LITHIUM ALUMINIUM HYDRIDE

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