107256-99-5

Basic information

• Product Name: tamoxifen methiodide
• Synonyms: tamoxifen methiodide
• CAS NO: 107256-99-5
• Molecular Formula: C₂₇H₃₂NO*I
• Molecular Weight: 0
• Mol File: 107256-99-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: tamoxifen methiodide(CAS DataBase Reference)
• NIST Chemistry Reference: tamoxifen methiodide(107256-99-5)
• EPA Substance Registry System: tamoxifen methiodide(107256-99-5)

Safety Data

• Hazardous Substances Data: 107256-99-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C27H32NO.HI/c1-5-26(22-12-8-6-9-13-22)27(23-14-10-7-11-15-23)24-16-18-25(19-17-24)29-21-20-28(2,3)4;/h6-19H,5,20-21H2,1-4H3;1H/q+1;/p-1/b27-26-;

Upstream product

• 10540-29-1 tamoxifen 
• 74-88-4 methyl iodide 

Relevant articles and documents

Calixarene-mediated liquid membrane transport of choline conjugates 2: Transport of drug-choline conjugates and neurotransmitters

Lower rim carboxylic acid calix[n]arenes and upper rim phosphonic acid functionalized calix[4]arenes effect selective transport of distinct molecular payloads through a liquid membrane. The secret to this success lies in the attachment of a receptor-complementary handle. We find that the trimethylammonium ethylene group present in choline is a general handle for the transport of drug and drug-like species. Furthermore, neurotransmitters possessing ionizable amine termini are also transported. Some limitations to this strategy have been uncovered as payloads become increasingly lipophilic. These developments reveal new approaches to synthetic receptor-mediated selective small molecule transport in vesicular and cellular systems. Ammonium species emerge as general and potent handles for effecting drug transport as mediated by ionizable calixarenes. Trimethylammonium, ammonium and ammonium carboxylates work in conjunction with phosphonic acid and carboxylic acid functionalized calix[n]arenes.