1071-37-0

Basic information

• Product Name: S-ETHYLISOTHIOUREA HYDROBROMIDE
• Synonyms: S-ETHYLTHIOUREAHYDROBROMIDE;S-Ethyl isothiouronium bromide, 98+%;2-Ethyl-thiopseudourea Hydrobromide;2-Ethyl-2-thio-pseudourea MonohydrobroMide;CarbaMiMidothioic Acid Ethyl Ester, HydrobroMide;S-EthylisothiouroniuM HydrobroMide;S-Ethylisothiourea Hydrobromide;2-ethyl-2-thio-pseudourehydrobromide
• CAS NO: 1071-37-0
• Molecular Formula: BrH*C₃H₈N₂S
• Molecular Weight: 185.09
• EINECS: 210-899-3
• Product Categories: Metal Isotopes;Sulfur & Selenium Compounds
• Mol File: 1071-37-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 79-81°C
• Boiling Point: 159.6 °C at 760 mmHg
• Flash Point: 50.3 °C
• Appearance: White/Crystalline Powder
• Density: 1.09g/cm³
• Vapor Pressure: 2.26mmHg at 25°C
• Refractive Index: 1.548
• Storage Temp.: 2-8°C
• Solubility: DMSO (Slightly), Methanol (Slightly, Heated)
• CAS DataBase Reference: S-ETHYLISOTHIOUREA HYDROBROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: S-ETHYLISOTHIOUREA HYDROBROMIDE(1071-37-0)
• EPA Substance Registry System: S-ETHYLISOTHIOUREA HYDROBROMIDE(1071-37-0)

Safety Data

• Statements: 22
• Safety Statements: 22-36/37
• WGK Germany: 3
• RTECS: UM6825000
• Hazardous Substances Data: 1071-37-0(Hazardous Substances Data)

Usage

Description

S-Ethylisothiourea Hydrobromide, with the CAS number 1071-37-0, is a white crystalline solid that is primarily used in organic synthesis. It is also utilized in the production of dyes and metabolites, making it a versatile compound in the chemical industry.

Uses

Used in Organic Synthesis:
S-Ethylisothiourea Hydrobromide is used as a synthetic building block for the creation of various organic compounds. Its unique chemical structure allows it to be a valuable intermediate in the synthesis of a wide range of molecules, contributing to the development of new pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Dye Production:
In the dye industry, S-Ethylisothiourea Hydrobromide is used as a key component in the production of various dyes. Its chemical properties enable the creation of dyes with specific color characteristics, making it an essential compound in the formulation of dyes for textiles, plastics, and other applications.
Used in Metabolite Synthesis:
S-Ethylisothiourea Hydrobromide is also employed in the synthesis of metabolites, which are intermediates or products of metabolism. These metabolites can be used in research and development for understanding biological processes, drug discovery, and the creation of diagnostic tools.

InChI:InChI=1/C3H8N2S/c1-2-5-3(4)6/h2H2,1H3,(H3,4,5,6)

Upstream product

• 74-96-4 ethyl bromide 
• 17356-08-0 thiourea 

Downstream Products

• 13429-32-8 N-(2-hydroxy-ethyl)-N-methyl-guanidine 
• 18431-52-2 1-amino-5-guanidinopentane 
• 5070-04-2 1,5-Diguanidino-pentan 
• 13551-09-2 N,N'-diguanyl-L-cystine 
• 62476-84-0 1,1'-(propane-1,3-diyl)diguanidine 
• 1190-74-5 N-(2-mercaptoethyl)guanidine 
• 352-97-6 guanidineacetic acid 
• 4884-56-4 3H-2-ethylthio-6-phenyl-6,7-dihydrothieno<3,2-d>pyrimidin-4-one 
• 127181-80-0 (1S,3R,4R,6R)-4-Ethylsulfanyl-3,7,7-trimethyl-bicyclo[4.1.0]heptan-3-ol 
• 107583-04-0 3'-Benzylspiro-2,2',5(3'H)-trione 
• 107582-74-1 dl-6-chloro-3-methyl-spiro[1,2,3,4-tetrahydroquinazoline-4,4'-imidazolidine]-2,2',5'-trione 
• 811-51-8 sodium thioethylate 
• 34245-63-1 5'-<(aminoiminomethyl)amino>-2',3'-(1-methylethylidene)-5'-deoxyadenosine 
• 23460-46-0 (Z,Z)-1,4-di(ethylthio)-1,4-diphenyl-1,3-butadiene 

Relevant articles and documents

Rapid access to novel 2-alkylthiopyrimidine derivatives and attempt of their Tacrine analogs synthesis

A variety of novel 2-alkylthiopyrimidines were synthesized through simple condensation of arylidenemalononitriles with different 2-alkylthiouronium halide derivatives catalyzed by anhydrous potassium carbonate (K2CO3). The reactions have been carried out under mild conditions in i-PrOH, and the products were obtained in moderate to good yields with a simple work-up method. Subsequently, some examples of these compounds have been converted into Tacrine analogs by applying the Friedl?nder reaction.

Convenient and environment-friendly synthesis of sulfonyl chlorides from S -alkylisothiourea salts via N-chlorosuccinimide chlorosulfonation

A convenient, practical, and environmentally friendly method for the synthesis of sulfonyl chlorides has been developed. Structurally diverse sulfonyl chlorides were synthesized in moderate to excellent yields from S-alkylisothiourea salts, which can be easily prepared from readily accessible alkyl halides or mesylates and inexpensive thiourea, via N-chlorosuccinimide chlorosulfonation. In large-scale syntheses, the byproduct succinimide from 'waste water' can be conveniently converted into the starting reagent N-chlorosuccinimide with sodium hypochlorite (bleach) to make the method sustainable. Georg Thieme Verlag Stuttgart, New York.

EFFECT OF VICINAL SUBSTITUENTS ON THE REACTIVITY IN BIMOLECULAR NUCLEOPHILIC SUBSTITUTION AT A SATURATED CARBON ATOM. TWO TYPES OF SUBSTITUENTS II. KINETICS OF THE REACTION OF THIOUREA WITH β-SUBSTITUTED BROMOETHANES IN ETHANOL

The kinetics of the reaction of thiourea with β-substituted bromoethanes in ethanol were studied by radiochromatography.The rate constants and activation parameters of the reactions were determined.It was shown that an isokinetic relationship is observed for the two types of substituents.The mechanisms of the effect of the vicinal substituents on the reactivity are discussed.