1060759-64-9Relevant articles and documents
Design and synthesis of novel C14-hydroxyl substituted triptolide derivatives as potential selective antitumor agents
Li, Zheng,Zhou, Zhao-Li,Miao, Ze-Hong,Lin, Li-Ping,Feng, Hui-Jin,Tong, Lin-Jiang,Ding, Jian,Li, Yuan-Chao
, p. 5115 - 5123 (2009)
It has long been considered that the free β hydroxyl group at C14 of triptolide (1) is essential to its potent anticancer activity. In this study, we synthesized novel derivatives of 1 with a hydroxyl group substituted by epoxy groups (4-8) or a five-memb
