10592-65-1

Basic information

• Product Name: Quingestanol
• Synonyms: Quingestanol;(17R)-3-Cyclopentyloxy-19-norpregna-3,5-dien-20-yn-17-ol
• CAS NO: 10592-65-1
• Molecular Formula: C25H34O2
• Molecular Weight: 366.5363
• EINECS: 234-199-2
• Mol File: 10592-65-1.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 520.2°Cat760mmHg
• Flash Point: 230°C
• Appearance: /
• Density: 1.13g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.583
• CAS DataBase Reference: Quingestanol(CAS DataBase Reference)
• NIST Chemistry Reference: Quingestanol(10592-65-1)
• EPA Substance Registry System: Quingestanol(10592-65-1)

Safety Data

• Hazardous Substances Data: 10592-65-1(Hazardous Substances Data)

Usage

Uses

Progestin.

InChI:InChI=1/C25H34O2/c1-3-25(26)15-13-23-22-10-8-17-16-19(27-18-6-4-5-7-18)9-11-20(17)21(22)12-14-24(23,25)2/h1,8,16,18,20-23,26H,4-7,9-15H2,2H3/t20-,21+,22+,23-,24-,25-/m0/s1

Related news

Clinical experience in India with a once-a-month oral contraceptive pill: Quingestanol (cas 10592-65-1) and quinestrol08/21/2019

The results of several studies have shown favourable results with a once-a-month pill containing 2.5 mg quingestanol acetate and 2 mg quinestrol. In a multicentre study, 666 women were investigated for 3,130 woman months. Data analyzed using life-table method indicated a net cumulative continuat...detailed

The evaluation of Quingestanol (cas 10592-65-1) acetate as a low dose oral contraceptive08/19/2019

Four hundred patients completed 4,370 cycles of treatment using quingestanol acetate, 300 mcg daily. Twelve pregnancies occurred resulting in a failure rate of 3.3 per 100 woman years. Seven of these pregnancies were considered drug failures giving a rate of 1.9 per 100 woman years. Cycle length...detailed

Continuous microdose (0.3 mg) Quingestanol (cas 10592-65-1) acetate as an oral contraceptive agent08/18/2019

Quingestanol acetate, an oral progestin, was administered in a continuous daily dose of 0.3 mg to 382 healthy women for a total of 3,208 woman-months, for contraceptive purposes. There was a cumulative pregnancy rate of 2.9 percent and a cumulative continuation rate of only 50 percent at the end...detailed

Further experience with Quingestanol (cas 10592-65-1) acetate as a postcoital oral contraceptive08/17/2019

A previous report based on investigations in Mexico suggested that quingestanol acetate might have potential as a postcoital oral contraceptive at a 800 mcg dose. This concept was based on some 1,000 cycles of therapy with no pregnancies in patients preselected to have 2 to 4 coital acts per wee...detailed

DRUG STANDARDSSeparation of Quingestanol (cas 10592-65-1) Acetate from Sesame Oil Solution and Its Determination in Combinations withEthinyl Estradiol or Quinestrol08/15/2019

Quingestanol acetate, norethindrone acetate 3-cyclopentyl enol ether, was not separable from its sesame oil dosage form vehicle as the intact compound using chromatography procedures that depend on differences in polarity. The steroid can be retained quantitatively on a Florisil column treated w...detailed

Effects of Quingestanol (cas 10592-65-1) acetate on the histology, histochemistry, and ultrastructure of the human endometrium08/14/2019

Quingestanol acetate is a potent progestogen which significantly alters the histology and histochemistry of the endometrium when studied by light and electron microscopy. The steroid did not alter transport mechanisms across the cell surfaces but, probably because of competition with estrogen fo...detailed