105601-88-5

Basic information

• Product Name: 1-Pyrrolidinecarboxylic acid, 3-hydroxy-, (4-nitrophenyl)methyl ester, (3R)-
• CAS NO: 105601-88-5
• Molecular Formula: C12H14N2O5
• Molecular Weight: 266.254
• Mol File: 105601-88-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Pyrrolidinecarboxylic acid, 3-hydroxy-, (4-nitrophenyl)methyl ester, (3R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolidinecarboxylic acid, 3-hydroxy-, (4-nitrophenyl)methyl ester, (3R)-(105601-88-5)
• EPA Substance Registry System: 1-Pyrrolidinecarboxylic acid, 3-hydroxy-, (4-nitrophenyl)methyl ester, (3R)-(105601-88-5)

Safety Data

• Hazardous Substances Data: 105601-88-5(Hazardous Substances Data)

Upstream product

• 100295-67-8 (R)-Pyrrolidin-3-ol; compound with methanesulfonic acid 
• 4457-32-3 4-nitrobenzyl chloroformate 
• 104706-47-0 (R)-3-hydroxypyrrolidine hydrochloride 

Downstream Products

• 99520-91-9 3-(S)-methansulfonyloxy-1-p-nitrobenzyloxycarbonylpyrrolidine 
• 429671-46-5 (3S)-3-acetoxy-1-(p-nitrobenzyloxycarbonyl)pyrrolidine 
• 429671-36-3 (3S)-3-amino-1-(p-nitrobenzyloxycarbonyl)pyrrolidine 
• 429671-52-3 (3R)-3-amino-1-(p-nitrobenzyloxycarbonyl)pyrrolidine 
• 352305-55-6 7-[(3S)-1-(4-nitrobenzyloxycarbonyl)pyrrolidin-3-yl]thioimidazo[5,1-b]thiazole 
• 91319-84-5 3-(S)-acetylthio-1-p-nitrobenzyloxycarbonylpyrrolidine 
• 99520-87-3 3-(S)-hydroxy-1-p-nitrobenzyloxycarbonylpyrrolidine 
• 87657-41-8 (S)-3-mercapto-1-(p-nitrobenzyloxycarbonyl)pyrrolidine 
• 105601-90-9 3-(S)-benzoyloxy-1-p-nitrobenzyloxycarbonylpyrrolidine 
• 91319-85-6 3-(R)-methanesulfonyloxy-1-p-nitrobenzyloxycarbonylpyrrolidine 

Relevant articles and documents

1-Methylcarbapenem derivatives

1-Methylcarbapenem compounds having antibacterial activity, pharmacologically acceptable esters or salts thereof and pharmaceutical compositions (particularly antibacterial agents) containing them as an active ingredient are described. In addition, the invention includes the use of these compounds, ester derivatives or salts for the manufacture of pharmaceutical compositions, or a method for the prevention or treatment of diseases (particularly bacterial infections) by administering a pharmacologically effective amount of the compounds, ester derivatives or salts to warm-blooded animals (particularly human beings).

SYNTHESIS OF OPTICALLY ACTIVE 3-MERCAPTOPYRROLIDINE DERIVATIVES. SYNTHETIC INTERMEDIATES OF CARBAPENEM RS-533 AND ITS ISOMER

The optically active 3-mercaptopyrrolidine derivatives(3a, 3b, 4a and 4b), which are synthetic intermediates of the carbapenem RS-533 (2a) and its isomer (2b), were synthesized by convenient and practical methods.