105314-53-2

Basic information

• Product Name: (S)-N-methyl-3-(2-methylphenoxy)-3-phenyl-1-propanamine
• Synonyms: (S)-N-methyl-3-(2-methylphenoxy)-3-phenyl-1-propanamine
• CAS NO: 105314-53-2
• Molecular Weight: 255.36
• Mol File: 105314-53-2.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: (S)-N-methyl-3-(2-methylphenoxy)-3-phenyl-1-propanamine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-methyl-3-(2-methylphenoxy)-3-phenyl-1-propanamine(105314-53-2)
• EPA Substance Registry System: (S)-N-methyl-3-(2-methylphenoxy)-3-phenyl-1-propanamine(105314-53-2)

Safety Data

• Hazardous Substances Data: 105314-53-2(Hazardous Substances Data)

Usage

Description

(S)-N-methyl-3-(2-methylphenoxy)-3-phenyl-1-propanamine, a chemical compound belonging to the class of amphetamines, is a central nervous system stimulant with notable psychoactive effects. It is recognized for its ability to enhance alertness, energy, and induce euphoria. (S)-N-methyl-3-(2-methylphenoxy)-3-phenyl-1-propanamine has been investigated for its potential therapeutic applications in various conditions, including attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity.
Used in Pharmaceutical Industry:
(S)-N-methyl-3-(2-methylphenoxy)-3-phenyl-1-propanamine is used as a therapeutic agent for the treatment of ADHD, narcolepsy, and obesity due to its ability to increase the levels of neurotransmitters like dopamine and norepinephrine in the brain. These neurotransmitters play a crucial role in regulating attention, motivation, and reward pathways.
Used in Research and Development:
In the field of neuroscience and pharmacology, (S)-N-methyl-3-(2-methylphenoxy)-3-phenyl-1-propanamine is used as a research compound to study the effects of central nervous system stimulants on cognitive functions and behavior. This helps in understanding the underlying mechanisms of attention, motivation, and the potential for abuse and addiction.

Upstream product

• 95-49-8 2-methylchlorobenzene 
• 115290-81-8 (R)-N-methyl-3-phenyl-3-hydroxypropylamine 
• 115290-79-4 (R)-3-(2-methylphenoxy)-3-phenylprop-1-yl methanesulfonate 
• 74-89-5 methylamine 
• 114446-47-8 -(-)-1-chloro-3-phenyl-3-(2-methylphenoxy)propane 
• 118856-08-9 butyric acid 2-ethoxycarbonyl-1-phenyl-ethyl ester 
• 838841-85-3 (3S) ethyl β-butyryloxy-β-phenyl propionate 
• 71-43-2 benzene 
• 114133-37-8 (S)-N-methyl-3-amino-1-phenyl-1-propanol 
• 115290-80-7 (3S) 3-phenyl-3-(2-methylphenoxy)propyl methanesulfonate 
• 114446-50-3 -(+)-1-chloro-3-phenyl-3-(2-methylphenoxy)propane 
• 191733-28-5 (S)-N-(ethoxycarbonyl)-3-(2-methylphenoxy)-3-phenyl-1-propanamine 
• 72656-47-4 ethyl (R)-3-hydroxy-3-phenylpropanoate 
• 96854-34-1 (S)-3-phenyl-1,3-propanediol 

Downstream Products

• 82857-39-4 -(+)-tomoxetine hydrochloride 
• 1027094-45-6 (R)-atomoxetine oxalate 
• 63940-51-2 (+/-)-atomoxetine 
• 105314-52-1 (R)-tomoxetine 
• 134619-78-6 (-)-N-tert-butoxycarbonyl-N-methyl-3-phenyl-3-(2-methylphenoxy)propanamine 
• 851086-84-5 S-rivastigmine-atomoxetine 
• 82248-59-7 atomoxetine hydrochloride 

Relevant articles and documents

Preparation method of cefamoxetine hydrochloride

The invention discloses a preparation method of tamoxidectin hydrochloride, belongs to the technical field of drug synthesis, and uses 3 - chlorine -1 - phenylpropanone as a raw material to undergo a reduction reaction. The synthesis route has the advantages of few reaction steps, mild reaction conditions,3 - simple 2 - operation, cheap -3 - and easily available raw materials, and low production cost 3 - and -1 - R-chloro - N - phenylpropanone is used as a raw material.

Preparation method of atomoxetine hydrochloride

The invention belongs to the technical field of medicines, and particularly relates to a preparation method of atomoxetine hydrochloride serving as a medicine for treating attention deficit hyperactivity. According to the invention, commercially available (E)-N-methyl-3-phenyl-2-propylene-1-amine is adopted as a starting material, and addition, substitution and salification are carried out so as to prepare atomoxetine hydrochloride. The preparation method provided by the invention is simple in preparation process, simple and convenient to operate, relatively high in yield and suitable for industrial production, and can provide sufficient bulk drugs for research and development of medicines.

Preparation method of atomoxetine

The invention belongs to the technical field of medicines, and particularly relates to a preparation method of atomoxetine hydrochloride serving as a medicine for treating attention deficit hyperactivity. Commercially available 3-(methylamino)-1-phenylacetone is adopted as a starting material, and undergoes asymmetric reduction, substitution and other reactions to prepare the atomoxetine. The invention mainly aims to prepare the atomoxetine by an asymmetric synthesis method and expand a preparation method of the atomoxetine hydrochloride.