105089-87-0

Basic information

• Product Name: 1-Pyrrolidinecarboxylic acid, 2-[bis(ethylthio)methyl]-, phenylmethyl ester, (S)-
• CAS NO: 105089-87-0
• Molecular Formula: C17H25NO2S2
• Molecular Weight: 339.523
• Mol File: 105089-87-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Pyrrolidinecarboxylic acid, 2-[bis(ethylthio)methyl]-, phenylmethyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolidinecarboxylic acid, 2-[bis(ethylthio)methyl]-, phenylmethyl ester, (S)-(105089-87-0)
• EPA Substance Registry System: 1-Pyrrolidinecarboxylic acid, 2-[bis(ethylthio)methyl]-, phenylmethyl ester, (S)-(105089-87-0)

Safety Data

• Hazardous Substances Data: 105089-87-0(Hazardous Substances Data)

Upstream product

• 71461-30-8 (S)-2-formylpyrrolidine-1-carboxylic acid benzyl ester 
• 75-08-1 ethanethiol 
• 147-85-3 L-proline 
• 501-53-1 benzyl chloroformate 
• 6216-63-3 N-Cbz-Prolinol 
• 1148-11-4 N-Benzyloxycarbonyl-L-proline 
• 5211-23-4 N-carbobenzyloxy-L-proline methyl ester 
• 61350-60-5 (S)-benzyloxycarbonyl-proline acid chloride 

Downstream Products

• 1370531-40-0 (2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolyl[4-(6-methoxy-1,3-benzothiazol-2-yl)-2-nitrophenyl]methanone 
• 1370531-41-1 (2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolyl[4-(6-fluoro-1,3-benzothiazol-2-yl)-2-nitrophenyl]methanone 
• 1370531-42-2 [4-(1,3-benzothiazol-2-yl)-2-nitrophenyl](2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolylmethanone 
• 1370531-43-3 1[2-amino-4-(6-methoxy-1,3-benzothiazol-2-yl)phenyl](2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolylmethanone 
• 1370531-44-4 [2-amino-4-(6-fluoro-1,3-benzothiazol-2-yl)phenyl](2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolylmethanone 
• 1370531-45-5 [2-amino-4-(1,3-benzothiazol-2-yl)phenyl](2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolylmethanone 
• 105089-65-4 (2S)-N-(2-nitrobenzoyl)pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 105089-66-5 (2S)-N-(2-aminobenzoyl)pyrrolidine-2-carboxaldehyde diethyl thioacetal 
• 72435-89-3 (11aS)-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one 

Relevant articles and documents

Hybrids of privileged structures benzothiazoles and pyrrolo[2,1-c] [1,4]benzodiazepin-5-one, and diversity-oriented synthesis of benzothiazoles

Privileged structures like Benzothiazole and Pyrrolobenzodiazepine offer wonderful opportunity to explore in anti-cancer drug discovery as a mean to counter drug-resistance problem. BT-PBD hybrids and diverse BT derivatives have been synthesized and their in vitro cytotoxic activities were screened against five cancer cell lines have been discussed. The novel compounds showed promising results as compared with the marketed drug etoposide and could well be used in future anti-cancer drug development studies.