1048374-12-4Relevant articles and documents
Evaluation of 2′-α-fluorine modified nucleoside phosphonates as potential inhibitors of HCV polymerase
Parrish, Jay P.,Lee, Sharon K.,Boojamra, Constantine G.,Hui, Hon,Babusis, Darius,Brown, Brandon,Shih, I-Hung,Feng, Joy Y.,Ray, Adrian S.,Mackman, Richard L.
, p. 3354 - 3357 (2013/06/27)
Ribonucleoside phosphonate analogues containing 2′-α-fluoro modifications were synthesized and their potency evaluated against HCV RNA polymerase. The diphosphophosphonate (triphosphate equivalent) adenine and cytidine analogues displayed potent inhibitio