1040400-87-0 Usage
General Description
2-AMINO-5-FLUOROBENZENEBORONIC ACID is a chemical compound with the molecular formula C6H7BFNO2. It is a boronic acid derivative with a fluorine and amino group attached to a benzene ring. 2-AMINO-5-FLUOROBENZENEBORONIC ACID is often used in organic synthesis and medicinal chemistry as a building block for the preparation of various pharmaceuticals and agrochemicals. It is also commonly used as a reagent in Suzuki-Miyaura coupling reactions, which is a popular method for forming carbon-carbon bonds in organic synthesis. Additionally, 2-AMINO-5-FLUOROBENZENEBORONIC ACID has been studied for its potential therapeutic applications, including as a potential treatment for cancer and other diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 1040400-87-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,0,4,0 and 0 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1040400-87:
(9*1)+(8*0)+(7*4)+(6*0)+(5*4)+(4*0)+(3*0)+(2*8)+(1*7)=80
80 % 10 = 0
So 1040400-87-0 is a valid CAS Registry Number.
1040400-87-0Relevant articles and documents
Synthesis and evaluation of the tetracyclic ring-system of isocryptolepine and regioiso-mers for antimalarial, antiproliferative and antimicrobial activities
Albrigtsen, Marte,Andersen, Jeanette H.,Avery, Vicky M.,H?heim, Katja S.,Helgeland, Ida T. Urdal,Kennedy, Emily K.,Lauga, Clémence,Lindb?ck, Emil,Matringe, Théodora,Sydnes, Magne O.,Tan, Kah Ni
, (2021/06/16)
A series of novel quinoline-based tetracyclic ring-systems were synthesized and evaluated in vitro for their antiplasmodial, antiproliferative and antimicrobial activities. The novel hydroiodide salts 10 and 21 showed the most promising antiplasmodial inhibition, with compound 10 displaying higher selectivity than the employed standards. The antiproliferative assay revealed novel pyridophenanthridine 4b to be significantly more active against human prostate cancer (IC50 = 24 nM) than Puromycin (IC50 = 270 nM) and Doxorubicin (IC50 = 830 nM), which are used for clinical treatment. Pyridocarbazoles 9 was also moderately effective against all the employed cancer cell lines and moreover showed excellent biofilm inhibition (9a: MBIC = 100 μM; 9b: MBIC = 100 μM).
