1033225-45-4Relevant articles and documents
Development of a pilot-plant-scale synthesis of an alkylated dihydrobenzothiadiazole S, S-dioxide: Incorporation of a late-stage mitsunobu reaction
Connolly, Terrence J.,Auguscinski, Waldemar,Fung, Peter,Galante, Rocco,Liu, Weiguo,McGovern, Linda,Sebastian, Alice,Shen, Xiaole,Shi, Xinxu,Wilk, Boguslawa,Varsalona, Richard,Zhong, Huijuan
, p. 868 - 877 (2011/03/20)
The process used to prepare a functionalized dihydrobenzothiadiazole S,S-dioxide on a pilot plant scale is described. Key changes to the original synthesis included: modifying SNAr reaction conditions between a substituted aniline and 2-fluoron
ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE
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Page/Page column 136-137, (2008/12/06)
The present invention is directed to aryl sulfamide derivatives of formula (I): or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions, including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal disorders and genitourinary disorder, depression disorders, endogenous behavioral disorders, cognitive disorders, diabetic neuropathy, pain, and other diseases or disorders.