1026417-80-0Relevant articles and documents
Synthesis and evaluation of trimetoquinol derivatives: Novel thromboxane A2/prostaglandin H2 antagonists with diminished β-adrenergic agonist activity
Christoff, Jeffrey J.,Bradley, Luke,Miller, Duane D.,Lei, Longping,Rodriguez, Fernando,Fraundorfer, Paul,Romstedt, Karl,Shams, Gamal,Feller, Dennis R.
, p. 85 - 91 (2007/10/03)
Trimetoquinol (TMQ, 1) is a unique catecholamine with a strong stereodependence for agonism at β-adrenergic (S >> R) and antagonism at thromboxane A2/prostaglandin H2 (TP; R >> S) receptors. Our laboratory has reported the effects of