102310-99-6

Basic information

• Product Name: 1,3,5-Triazine, 1,3,5-tris(4-bromophenyl)hexahydro-
• CAS NO: 102310-99-6
• Molecular Formula: C21H18Br3N3
• Molecular Weight: 552.106
• Mol File: 102310-99-6.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: 1,3,5-Triazine, 1,3,5-tris(4-bromophenyl)hexahydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,5-Triazine, 1,3,5-tris(4-bromophenyl)hexahydro-(102310-99-6)
• EPA Substance Registry System: 1,3,5-Triazine, 1,3,5-tris(4-bromophenyl)hexahydro-(102310-99-6)

Safety Data

• Hazardous Substances Data: 102310-99-6(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 106-40-1 4-bromo-aniline 
• 51-46-7 1,3,6,8-tetraazatricyclo[4.4.1.1^3,8]dodecane 
• 108-73-6 3,5-dihydroxyphenol 
• 64-17-5 ethanol 
• 856192-74-0 N,N'-bis-(4-bromo-phenyl)-methylenediamine 

Downstream Products

• 854635-71-5 N-(2-amino-5-bromo-benzyl)-4-bromo-aniline 
• 32328-81-7 4-bromo-N-methylen-aniline 
• 109423-18-9 Trifluoro-acetic acid [(4-bromo-phenyl)-(2,2,2-trifluoro-acetyl)-amino]-methyl ester 
• 1173196-78-5 ethyl 1-(4-bromophenyl)-4-((4-bromophenyl)amino)-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate 

Relevant articles and documents

Preparation of spiro[imidazolidine-4,3′-indolin]-2′-imines: Via copper(i)-catalyzed formal [2 + 2 + 1] cycloaddition of 3-diazoindolin-2-imines and triazines

We report a facile and efficient synthesis of spiro[imidazolidine-4,3′-indolin]-2′-imines via a copper(i)-catalyzed cascade reaction of 3-diazoindolin-2-imines with 1,3,5-triazines. The reaction proceeds under very mild conditions and tolerates a variety of functional groups. The cascade process involves the formation of a copper-carbene intermediate and a formal [2 + 2 + 1] cycloaddition.

Activation Relay on Rhodium-Catalyzed C-H Aminomethylation in Cooperation with Photoredox Catalysis

A site selective C-H aminomethylation at indole's C3 position has been achieved by merging rhodium(III)-catalyzed C-H activation and photoredox catalysis in a one-pot manner. An investigation of the mechanistic insights rationalized the essence of the activation relay and the combination mode.

Gold-Catalyzed Tandem Dual Heterocyclization of Enynones with 1,3,5-Triazines: Bicyclic Furan Synthesis and Mechanistic Insights

A general and unprecedented gold-catalyzed tandem dual heterocyclization reaction of enynones with 1,3,5-triazines has been developed, which provides bicyclic fused furans in high to excellent yields under mild reaction conditions. In addition, mechanistic studies indicate that the reaction goes through a stepwise [3+2+2]-cycloaddition of furanyl gold intermediate, which is generated from gold-catalyzed cyclization of enynone, with two molecules of formaldimines derived in situ from 1,3,5-triazine, instead of formal [4+3]-cycloaddition.

Synthesis of Diversely Substituted Imidazolidines via [3+2] Cycloaddition of 1,3,5-Triazinanes with Donor-Acceptor Aziridines and Their Anti-Tumor Activity

A Y(OTf)3-catalyzed [3+2] cycloaddition of 1,3,5-triazinanes with donor-acceptor aziridines has been developed, accessing diversely substituted imidazolidines high efficiency. Mechanistic investigations support the formation of imidazolidines through an SN1-like pathway. Furthermore, these imidazolidines exhibit promising anti-tumor activity against a series of human cancer cell lines. (Figure presented.).

Synthesis of α-Amino Tertiary Alkylperoxides by Lewis Acid-Catalyzed Peroxidation of 1,3,5-Triazines

α-Substituted peroxides have been found in natural products and are widely used as anti-malarial agents. Zn(OTf)2-catalyzed peroxidation of 1,3,5-triazines has been developed, accessing diversely substituted α-amino tertiary alkylperoxides with high efficiency. Mechanistic investigations and useful synthetic application of the products have also been presented.