102195-80-2

Basic information

• Product Name: BOC-4-OXO-PRO-OME
• Synonyms: BOC-PRO-(4-KETO)-OME;BOC-4-OXO-PRO-OME;BOC-4-OXO-L-PROLINE METHYL ESTER;BOC-GAMMA-KETO-L-PROLINE METHYL ESTER;BOC-L-PRO(4-O)-OME;BOC-L-PRO(4-OXO)-OME;(S)-N-ALPHA-TERT-BUTYLOXYCARBONYL-4-OXO-PROLINE METHYL ESTER;N-T-BOC-4-OXO-L-PROLINE METHYL ESTER
• CAS NO: 102195-80-2
• Molecular Formula: C₁₁H₁₇NO₅
• Molecular Weight: 243.26
• EINECS: 1308068-626-2
• Product Categories: Amino Acids;Boc-Amino Acids and Derivative;Boc-Amino acid series;Amino Acids & Derivatives;Heterocycles
• Mol File: 102195-80-2.mol
• Article Data: 78

Chemical Properties

• Melting Point: 35-40°C
• Boiling Point: 333.149 °C at 760 mmHg
• Flash Point: 110 °C
• Appearance: /
• Density: 1.21 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.488
• Storage Temp.: ?20°C
• PKA: -3.86±0.40(Predicted)
• CAS DataBase Reference: BOC-4-OXO-PRO-OME(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-4-OXO-PRO-OME(102195-80-2)
• EPA Substance Registry System: BOC-4-OXO-PRO-OME(102195-80-2)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-41
• Safety Statements: 26-36/37-39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 102195-80-2(Hazardous Substances Data)

Usage

Description

BOC-4-OXO-PRO-OME, also known as (2S)-1-Boc-4-oxo-proline Methyl Ester, is a chemical compound with the CAS number 102195-80-2. It is a yellow solid and is primarily used in organic synthesis due to its unique chemical properties.

Uses

Used in Organic Synthesis:
BOC-4-OXO-PRO-OME is used as a synthetic building block for the creation of various organic compounds. Its chemical structure allows it to be a versatile component in the synthesis of complex molecules, making it a valuable asset in the field of organic chemistry.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, BOC-4-OXO-PRO-OME is used as an intermediate in the development of new drugs. Its unique properties enable it to be a key component in the synthesis of potential therapeutic agents, contributing to the advancement of medical treatments.
Used in Chemical Research:
BOC-4-OXO-PRO-OME is also utilized in chemical research as a model compound for studying various reaction mechanisms and understanding the behavior of similar molecules. This helps researchers gain insights into the properties and reactivity of related compounds, furthering the knowledge in the field of chemistry.

InChI:InChI=1/C11H17NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h8H,5-6H2,1-4H3/t8-/m0/s1

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 178962-09-9 methyl (2R,4S)-4-hydroxypyrrolidine-2-carboxylate 
• 796095-60-8 (2S)-1-tert-butoxycarbonyl-2-(methoxycarbonyl)-4-hydroxyazacyclopentane 
• 1001383-50-1 trans-4-hydroxy-L-proline methyl ester 
• 51-35-4 4-hydroxyproline 
• 84348-37-8 N-tert-butoxycarbonyl-4-oxo-L-proline 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 1063998-64-0 (2S,4R)-4-Hydroxy-pyrrolidine-2-carbonyl chloride 
• 13726-69-7 (2S,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid 
• 7529-22-8 4-methylmorpholine N-oxide 
• 79-37-8 oxalyl dichloride 
• 67-68-5 dimethyl sulfoxide 
• 876317-19-0 ⁽²⁸⁾-1-(tert-butoxycarbonyl)-4-oxo-2-pyrrolidinecarboxylic acid 
• 51-35-4 4R-4-hydroxyproline 

Downstream Products

• 84348-39-0 (S)-1-tert-butyl 2-methyl 4-methylenepyrrolidine-1,2-dicarboxylate 
• 487-79-6 (-)-kainic acid 
• 1419387-85-1 C₄₇H₅₆F₄N₄O₁₂ 
• 1419391-59-5 C₄₅H₅₄N₂O₁₀ 
• 1352393-34-0 C₄₁H₄₇N₇O₅ 
• 1352393-33-9 (S)-tert-butyl 2-(5-(4-((4-(2-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)phenyl)ethynyl)phenyl)-1H-imidazol-2-yl)-4-methyl-2,5-dihydro-1H-pyrrole-1-carboxylate 
• 1352393-14-6 (S)-tert-butyl 4-methyl-2-(5-(4-((trimethylsilyl)ethynyl)phenyl)-1H-imidazol-2-yl)-2,5-dihydro-1H-pyrrole-1-carboxylate 
• 1352393-15-7 (S)-tert-butyl 2-(5-(4-ethynylphenyl)-1H-imidazol-2-yl)-4-methyl-2,5-dihydro-1H-pyrrole-1-carboxylate 
• 1352393-13-5 (S)-tert-butyl 2-(5-(4-bromophenyl)-1H-imidazol-2-yl)-4-methyl-2,5-dihydro-1H-pyrrole-1-carboxylate 
• 1352393-12-4 (S)-4-methyl-2,5-dihydro-pyrrole-1,2-dicarboxylic acid 2-[2-(4-bromo-phenyl)-2-oxo-ethyl]ester 1-tert-butyl ester 
• 1352391-62-8 methyl N-[(2S)-1-[(2S)-2-{5-[6-(4-{2-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl]-4-methyl-2,5-dihydro-1H-pyrrol-2-yl]-1H-imidazol-5-yl}phenyl)naphthalen-2-yl]-1H-imidazol-2-yl}pyrrolidin-1-yl]3-methyl-1-oxobutan-2-yl]carbamate 
• 1352393-43-1 2-((S)-4-methyl-2,5-dihydro-1H-pyrrol-2-yl)-5-(4-(6-(2-((S)-pyrrolidin-2-yl)-1H-imidazol-5-yl)naphthalen-2-yl)phenyl)-1H-imidazole 
• 1352393-42-0 (S)-tert-butyl 2-(5-(4-(6-(2-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-1H-imidazol-5-yl)naphthalen-2-yl)phenyl)-1H-imidazol-2-yl)-4-methyl-2,5-dihydro-1H-pyrrole-1-carboxylate 
• 1352391-68-4 methyl N-[(2S)-1-[(2S)-2-{5-[4-(2-{2-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl]-4-methyl-2,5-dihydro-1H-pyrrol-2-yl]-1H-1,3-benzodiazol-6-yl}ethynyl)phenyl]-1H-imidazol-2-yl}pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate 

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