1021933-95-8 Usage
Description
Venlafaxine N-Oxide Impurity, also known as D,L-O-Desmethyl Venlafaxine N-Oxide, is a metabolite of the drug Venlafaxine (V120000(P)). Venlafaxine is a selective serotonin noradrenaline reuptake inhibitor (SNRI) that is commonly used as an antidepressant medication. The impurity is a byproduct formed during the synthesis or metabolism of the parent drug and may have different properties and applications.
Uses
Used in Pharmaceutical Industry:
Venlafaxine N-Oxide Impurity is used as a research compound for understanding the metabolism and pharmacokinetics of Venlafaxine. It helps in the development of improved drug formulations and the study of drug interactions.
Used in Quality Control:
Venlafaxine N-Oxide Impurity is used as a reference material in the quality control of Venlafaxine drug products. It aids in the identification, quantification, and assessment of impurities in the final drug product, ensuring its safety and efficacy.
Used in Drug Development:
Venlafaxine N-Oxide Impurity can be used in the development of new drugs with similar mechanisms of action or as a starting material for the synthesis of novel antidepressant compounds.
Used in Toxicology Studies:
The impurity may be utilized in toxicology studies to evaluate the potential side effects and safety profile of Venlafaxine and its related compounds. This information can be crucial in the development of safer and more effective medications.
Check Digit Verification of cas no
The CAS Registry Mumber 1021933-95-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,1,9,3 and 3 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1021933-95:
(9*1)+(8*0)+(7*2)+(6*1)+(5*9)+(4*3)+(3*3)+(2*9)+(1*5)=118
118 % 10 = 8
So 1021933-95-8 is a valid CAS Registry Number.
1021933-95-8Relevant articles and documents
ISOLATED HYDROXY AND N-OXIDE METABOLITES AND DERIVATIVES OF O-DESMETHYLVENLAFAXINE AND METHODS OF TREATMENT
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Page/Page column 48-49; sheet 4, (2008/12/05)
The present invention provides novel isolated compounds characterized as metabolites or derivatives of desmethylvenlafaxine including hydroxy-DV metabolites, hydroxy-DV-glucuronide metabolites, N-oxide-DV metabolites, and benzyl-hydroxy-DV metabolites. The invention includes pharmaceutical compositions comprising any of the metabolites or derivatives of the invention in combination with a pharmaceutically acceptable carrier or excipient. The invention also includes a method of treating at least one central nervous system disorder in a mammal comprising providing to a mammal in need thereof an effective amount of the compounds of the invention.
