1016232-92-0

Basic information

• Product Name: 3,3-AZETIDINEDIMETHANOL HYDROCHLORIDE
• Synonyms: 3,3-AZETIDINEDIMETHANOL HYDROCHLORIDE;[3(hydroxyMethyl)azetidin3yl]Methanol hydrochloride;Azetidine-3,3-diyldimethanol hydrochloride;3,3-Azetidinedimethanol HCl;3,3-AZETIDINEDIYLDIMETHANOL HCL;azetidine-3,3-dimethanol hydrochloride;3,3-azetidinediyldimethanol hydrochloride
• CAS NO: 1016232-92-0
• Molecular Formula: C₅H₁₁NO₂*ClH
• Molecular Weight: 153.60728
• Mol File: 1016232-92-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,3-AZETIDINEDIMETHANOL HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-AZETIDINEDIMETHANOL HYDROCHLORIDE(1016232-92-0)
• EPA Substance Registry System: 3,3-AZETIDINEDIMETHANOL HYDROCHLORIDE(1016232-92-0)

Safety Data

• Hazardous Substances Data: 1016232-92-0(Hazardous Substances Data)

Usage

General Description

3,3-Azetidinedimethanol hydrochloride, also known as Tris(dimethylamino)methanol hydrochloride, is a chemical compound that is used as a reagent in organic synthesis. It is a crystalline solid with a white to off-white color, and it is readily soluble in water and polar organic solvents. 3,3-AZETIDINEDIMETHANOL HYDROCHLORIDE is commonly used as a catalyst in various chemical reactions, particularly in the production of pharmaceuticals and agrochemicals. It functions as a highly efficient and selective catalyst for a wide range of chemical transformations, including asymmetric synthesis and carbon-carbon bond formation. It is also considered to be a safer alternative to other commonly used catalysts, as it is non-toxic and non-corrosive. Overall, 3,3-Azetidinedimethanol hydrochloride is a versatile and valuable chemical reagent with broad applications in organic chemistry.

Upstream product

• 642411-11-8 3,3‐diethyl 1‐benzylazetidine‐3,3‐dicarboxylate 
• 26096-30-0 N-benzyl-3,3-bis-(hydroxymethyl)-azetidine 
• 45512-27-4 azetidine-3,3-dimethanol 

Downstream Products

• 1016233-34-3 1-[(7-benzyloxymethyl-4-tert-butoxy-9-deazapurin-9-yl)methyl]azetidine-3,3-dimethanol 
• 1016233-08-1 3,3-bis(hydroxymethyl)azetidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

AZETIDINE ANALOGUES OF NUCLEOSIDASE AND PHOSPHORYLASE INHIBITORS

Azetidine analogues of nucleosidase and nucleoside phosphorylase inhibitors having the general formula (I), the use of these compounds as pharmaceuticals, pharmaceutical compositions containing the compounds, methods of treating certain diseases using the compounds, processes for preparing the compounds, and intermediates useful in the preparation of the compounds wherein W and X are each independently selected from hydrogen, CH2OH, CH2OQ and CH2SQ; Y and Z are each independently selected from hydrogen, halogen, CH2OH, CH2OQ, CH2SQ, SQ, OQ and Q; Q is an alkyl, aralkyl or aryl group each of which may be optionally substituted with one or more substituents selected from hydroxy, halogen, methoxy, amino, or carboxy; R1 is a radical of the formula (II) or R1 is a radical of the formula (III) A is selected from N, CH and CR2, where R2 is selected from halogen, alkyl, aralkyl, aryl, OH, NH2, NHR3, NR3R4 and SR5, where R3, R4 and R5 are each alkyl, aralkyl or aryl groups optionally substituted with hydroxy or halogen, and where R2 is optionally substituted with hydroxy or halogen when R2 is alkyl, aralkyl or aryl; B is selected from hydroxy, NH2, NHR6, SH, hydrogen and halogen, where R6 is an alkyl, aralkyl or aryl group optionally substituted with hydroxy or halogen; D is selected from hydroxy, NH2, NHR7, hydrogen, halogen and SCH3, where R7 is an alkyl, aralkyl or aryl group optionally substituted with hydroxy or halogen; E is selected from N and CH; G is a C1-4 saturated or unsaturated alkyl group optionally substituted with hydroxy or halogen, or G is absent; or a tautomer thereof, or a pharmaceutically acceptable salt thereof, or an ester thereof, or a prodrug thereof.