101530-10-3 Usage
Description
Lanoconazole is a potent antifungal imidazole used for the treatment of dermal mycoses. It is an inhibitor of ergosterol biosynthesis, which alters the cell wall's ultra structure, and exhibits potent antifungal activity against a wide range of pathogenic fungi, including yeast, dermatophytes, dermatiaceous fungi, dimorphic fungi, Aspergillus spp., Penicillium spp., and Candida spp., with particular activity against Trichophyton spp. It is more potent than other agents of the same family, such as bifonazole and clotrimazole.
Uses
Used in Pharmaceutical Industry:
Lanoconazole is used as an antifungal agent for the treatment of various skin conditions caused by pathogenic fungi. It is particularly effective against Trichophyton spp. and has demonstrated clinical efficacy in improving skin symptoms of patients with tinea pedis, tinea corporis, cruris, candidiasis, and tinea versicolor.
Used in Antifungal Applications:
Lanoconazole is used as an antifungal agent to inhibit the growth of pathogenic fungi by disrupting ergosterol biosynthesis, which is essential for the integrity of the fungal cell wall. This action makes it a valuable tool in combating a wide range of fungal infections.
Chemical Properties:
Lanoconazole is characterized by its light-yellow crystal appearance.
Brand Name:
The brand name for Lanoconazole is Astat.
Originator
Nihon Nohyaku (Japan)
Check Digit Verification of cas no
The CAS Registry Mumber 101530-10-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,1,5,3 and 0 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 101530-10:
(8*1)+(7*0)+(6*1)+(5*5)+(4*3)+(3*0)+(2*1)+(1*0)=53
53 % 10 = 3
So 101530-10-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H10ClN3S2/c15-11-4-2-1-3-10(11)13-8-19-14(20-13)12(7-16)18-6-5-17-9-18/h1-6,9,13H,8H2/b14-12-
101530-10-3Relevant articles and documents
Method for treating mycosis using imidazolylacetonitrile derivatives
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, (2008/06/13)
R-(+)-(E)-?4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene!-1-imidazolylacetonitrile, R-(-)-(E)-?4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene!-1-imidazolylacetonitrile, and pharmaceutically acceptable salts thereof which can be used as a pharmaceutical agent are disclosed. A process for producing them and a method for treating mycoses using them are also disclosed.
Ketene S,S-acetal derivative, a process for manufacturing thereof and a method for curing mycosis by administering it
-
, (2008/06/13)
A novel ketene S,S-acetal derivative which is useful as an antimycotic agent and an agricultural chemical of fungicidal, plant growth regulating or insecticidal properties represented by the general formula (I): STR1 wherein R represents a hydrogen atom; an alkyl group having 1 to 8 carbon atoms; a cycloalkyl group having 3 to 6 carbon atoms; a methylene group; a lower alkenyl group; a lower alkyl group substituted by a halogen atom, a cyano group, a lower alkoxy group, a lower alkylthio group; a carbamoyl group, an acyl group, or an alkenoyloxy group; a phenyl group represented by STR2 (in which R1 represents a hydrogen atom, a halogen atom, a straight or branched chain lower alkyl group, a lower alkoxyl group which may be substituted by one or more halogen atoms, a phenoxy group or a methylenedioxy group, and m represents an integer of 1 to 3); a benzyl group; a methylenedioxybenzyl group; a phenoxyalkyl group; a phenoxyalkyl group substituted by a halogen atom; a naphthyl group; or a substituted or unsubstituted pyridyl group.
