100490-36-6

Basic information

• Product Name: TOSUFLOXACIN TOSILATE
• Synonyms: 1,8-naphthyridine-3-carboxylicacid,1,4-dihydro-7-(3-amino-1-pyrrolidinyl)-1-(;4-difluorophenyl)-6-fluoro-4-oxo-;a61827;a67107;abbott61827;1-(2,4-Difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-aminopyrrolidin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylic acid;1,8-Naphthyridine-3-carboxylic acid, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo- (9CI);(+)-7-(3-Amino-1-pyrrolidinyl)-6-fluoro-1-(2，4-difluo-rophenyl)-1，4-dihydrcr-4-oxo-1，8-naphthyridine-3-carboxyli cacid
• CAS NO: 100490-36-6
• Molecular Formula: C₁₉H₁₅F₃N₄O₃
• Molecular Weight: 576.54
• Mol File: 100490-36-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 614.4 °C at 760 mmHg
• Flash Point: 325.4 °C
• Appearance: White powder
• Density: 1.558 g/cm³
• Vapor Pressure: 5.96E-16mmHg at 25°C
• PKA: 5.79±0.70(Predicted)
• CAS DataBase Reference: TOSUFLOXACIN TOSILATE(CAS DataBase Reference)
• NIST Chemistry Reference: TOSUFLOXACIN TOSILATE(100490-36-6)
• EPA Substance Registry System: TOSUFLOXACIN TOSILATE(100490-36-6)

Safety Data

• Hazardous Substances Data: 100490-36-6(Hazardous Substances Data)

Usage

Description

TOSUFLOXACIN TOSILATE, with the CAS number 100490-36-6, is an active pharmaceutical ingredient that belongs to the class of fluoroquinolone antibiotics. It is known for its broad-spectrum antimicrobial activity and is effective against a variety of bacterial infections.

Uses

Used in Pharmaceutical Industry:
TOSUFLOXACIN TOSILATE is used as an antibiotic for treating bacterial infections. It works by inhibiting bacterial DNA replication and protein synthesis, leading to the disruption of bacterial cell function and ultimately resulting in cell death. This makes it a valuable component in the development of medications aimed at combating various bacterial pathogens.
Used in Antimicrobial Research:
In the field of antimicrobial research, TOSUFLOXACIN TOSILATE is utilized for studying its effectiveness against different strains of bacteria, such as the Haemophilus influenza clone ST422 mentioned in the provided materials. This research helps in understanding the antibiotic's potential applications and limitations in treating specific bacterial infections, contributing to the development of more targeted and effective treatments.

InChI:InChI=1/C19H15F3N4O3.C7H8O3S/c20-9-1-2-15(13(21)5-9)26-8-12(19(28)29)16(27)11-6-14(22)18(24-17(11)26)25-4-3-10(23)7-25;1-6-2-4-7(5-3-6)11(8,9)10/h1-2,5-6,8,10H,3-4,7,23H2,(H,28,29);2-5H,1H3,(H,8,9,10)

Relevant articles and documents

Naphthyridine antianaerobic compounds

The naphthyridine compounds having the formula: wherein R1 is hydrogen or a carboxy protecting group have unexpected and superior antianaerobic activity.